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CAS 1405-37-4

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Capreomycin sulfate

Description:
Capreomycin sulfate is an antibiotic compound primarily used in the treatment of tuberculosis, particularly in cases resistant to standard therapies. It is derived from the bacterium *Streptomyces capreolus* and exhibits a complex structure that includes a cyclic peptide and a fatty acid moiety. Capreomycin functions by inhibiting protein synthesis in bacteria, specifically targeting the ribosomal machinery, which ultimately leads to bacterial cell death. The sulfate form enhances its solubility in water, making it suitable for parenteral administration. Capreomycin is typically administered via injection and is often used in combination with other antitubercular agents to improve efficacy and reduce the risk of resistance. Its use is generally reserved for severe cases due to potential side effects, including nephrotoxicity and ototoxicity. As with many antibiotics, monitoring for adverse reactions and ensuring appropriate dosing is crucial for patient safety and treatment success.
Formula:H2O4S·Unspecified
InChI:InChI=1/C25H44N14O7.H2O4S/c1-11-19(41)36-15(9-32-17(40)7-12(27)3-2-5-26)21(43)37-16(10-34-25(30)46)22(44)39-18(14-4-6-31-24(29)38-14)23(45)33-8-13(28)20(42)35-11;1-5(2,3)4/h10-15,18H,2-9,26-28H2,1H3,(H,32,40)(H,33,45)(H,35,42)(H,36,41)(H,37,43)(H,39,44)(H3,29,31,38)(H3,30,34,46);(H2,1,2,3,4)/b16-10-;
InChI key:TUATYNXRYJTQTQ-BVRBKCERSA-N
SMILES:CC1C(=NC(CN=C(CC(CCCN)N)O)C(=N/C(=C\NC(=N)O)/C(=NC(C2CCNC(=N)N2)C(=NCC(C(=N1)O)N)O)O)O)O.OS(=O)(=O)O
Synonyms:
  • 3,6-diamino-N-[[(8Z)-15-amino-11-(2-iminohexahydropyrimidin-4-yl)-2-methyl-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide
  • Capastat sulfate
  • Capreomycin Sulfate
  • Capreomycin Sulphate
  • Capreomycin, sulfate (salt)
  • Caprocin
  • Sulfuric Acid
Found 11 products.