Anti-CD3 refers to a monoclonal antibody that targets the CD3 complex, a component of the T-cell receptor, which plays a crucial role in T-cell activation and immune response. The CAS number 140608-64-6 specifically identifies a particular form of this antibody. Anti-CD3 is primarily used in immunological research and therapeutic applications, particularly in the context of autoimmune diseases and organ transplantation, where modulation of T-cell activity is desired. This antibody can induce T-cell activation, leading to a cascade of immune responses, and is also utilized in clinical settings to promote tolerance in transplant patients. Characteristics of Anti-CD3 include its specificity for the CD3 epsilon chain, its ability to cross-link T-cell receptors, and its potential to influence cytokine production. The antibody is typically produced in hybridoma cell lines and can be administered in various forms, including as a recombinant protein. Its use is subject to careful regulation due to the profound effects it can have on the immune system.

Anti-CD3

140608-64-6: Anti-CD3 refers to a monoclonal antibody that targets the CD3 complex, a component of the T-cell receptor, which plays a crucial role in T-cell activation and immune response. The CAS number 140608-64-6 specifically identifies a particular form of this antibody. Anti-CD3 is primarily used in immunological research and therapeutic applications, particularly in the context of autoimmune diseases and organ transplantation, where modulation of T-cell activity is desired. This antibody can induce T-cell activation, leading to a cascade of immune responses, and is also utilized in clinical settings to promote tolerance in transplant patients. Characteristics of Anti-CD3 include its specificity for the CD3 epsilon chain, its ability to cross-link T-cell receptors, and its potential to influence cytokine production. The antibody is typically produced in hybridoma cell lines and can be administered in various forms, including as a recombinant protein. Its use is subject to careful regulation due to the profound effects it can have on the immune system.

Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.

CAS 140608-64-6

Anti-CD3

Muromonab

Ref: TM-T76719

Muromonab

Ref: 3D-CLA1107