CAS 140678-14-4

Manganate(6-), [[rel-[N(R),N′(R)]-N,N′-1,2-ethanediylbis[N-[[3-(hydroxy-κO)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-κN,κO]](8-)]-, sodium hydrogen (1:3:3), (OC-6-13)-

Description:

The chemical substance with the name "Manganate(6-), [[rel-[N(R),N′(R)]-N,N′-1,2-ethanediylbis[N-[[3-(hydroxy-κO)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-κN,κO]](8-)]-, sodium hydrogen (1:3:3), (OC-6-13)-" and CAS number "140678-14-4" is a complex coordination compound featuring manganese in a high oxidation state, specifically +6. This substance is characterized by its intricate ligand structure, which includes a bis-glycinate framework and a pyridine derivative, contributing to its potential biological activity and solubility properties. The presence of phosphonate groups suggests possible interactions with biological systems, making it of interest in medicinal chemistry and biochemistry. The sodium hydrogen component indicates that the compound may exhibit ionic characteristics, influencing its stability and reactivity in various environments. Overall, this compound's unique structure and functional groups may confer specific properties that could be exploited in various applications, including catalysis and drug design.

Formula: C₂₂H₂₄MnN₄O₁₄P₂·3H·3Na

InChI: InChI=1S/C22H32N4O14P2.Mn.3Na/c1-13-21(31)17(15(5-23-13)11-39-41(33,34)35)7-25(9-19(27)28)3-4-26(10-20(29)30)8-18-16(12-40-42(36,37)38)6-24-14(2)22(18)32;;;;/h5-6,31-32H,3-4,7-12H2,1-2H3,(H,27,28)(H,29,30)(H2,33,34,35)(H2,36,37,38);;;;/q;+2;3*+1/p-5

InChI key: InChIKey=BENFPBJLMUIGGD-UHFFFAOYSA-I

SMILES: O=C1[O-][Mn+2]2345[N](CC=6C([O-]2)=C(C)N=CC6COP(=O)([O-])[O-])(CC[N]3(CC=7C([O-]4)=C(C)N=CC7COP(=O)([O-])[O-])C1)CC(=O)[O-]5.[H+].[Na+]

Synonyms:

• Mangafodipir Trisodium [USAN]
• Manganate(6-), ((N,N'-1,2-ethanediylbis(N-((3-hydroxy-2-methyl-5-((phosphonooxy)-methyl)-4-pyridinyl)methyl)glycinato)) (8-))-, trisodium trihydrogen, (OC-6-13)-
• Manganate(6-), [[rel-[N(R),N′(R)]-N,N′-1,2-ethanediylbis[N-[[3-(hydroxy-κO)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-κN,κO]](8-)]-, sodium hydrogen (1:3:3), (OC-6-13)-
• Manganate(6-), [[rel-[N(R),N′(R)]-N,N′-1,2-ethanediylbis[N-[[3-(hydroxy-κO)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-κN,κO]](8-)]-, trisodium trihydrogen, (OC-6-13)-
• Manganese(2+) Sodium Hydrogen 2,2'-{Ethane-1,2-Diylbis[({2-Methyl-3-Oxido-5-[(Phosphonatooxy)Methyl]Pyridin-4-Yl}Methyl)Imino]}Diacetate (1:3:3:1)
• MnDPDP
• S 095
• Teslascan
• Trisodium trihydrogen (OC-6-13)-((N,N'-1,2-ethanediylbis(N-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycinato))(8-)manganate(6-)
• Trisodium trihydrogen (OC-6-13)-((N,N'-ethylenebis(N-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridyl)methyl)glycine) 5,5'-bis(phosphato))(8-))manganate(6-)
• Unii-129Fw80Tg4
• Win 59010
• Mangafodipir trisodium

MANGAFODIPIR TRISODIUM F0D2720.996MG/MG(AN)

CAS: 140678-14-4

Formula: C₂₂H₂₄MnN₄Na₃O₁₄P₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 757.3231

Ref: IN-DA009CIZ

Mangafodipir trisodium

CAS: 140678-14-4

Mangafodipir trisodium can enhance contrast in magnetic resonance imaging (MRI) of the liver, is a contrast agent delivered intravenously.

Formula: C₂₂H₂₇MnN₄Na₃O₁₄P₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 757.32

Ref: TM-T19413

Mangafodipir Trisodium

CAS: 140678-14-4

Formula: C₂₂H₂₇MnN₄Na₃O₁₄P₂

Molecular weight: 757.33

Ref: 4Z-M-222001

Mangafodipir Trisodium (>85%)

Controlled Product

CAS: 140678-14-4

Applications Mangafodipir Trisodium is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. It protects against hepatic ischemia-reperfusion injury in mice and decreases hematotoxicity and enhanced cytotoxicity of anticancer agents.
References Ben Mosbah, I., et al.: PLoS One, 7, e50235 (2012); Coriat, R., et al.: PLoS One, 6, e27005 (2011); Alexandre, J., et al.: J. Natl. Cancer I., 98, 236 (2006); Traore, A.S., et al.: Magn. Reson. Imaging, 21, 609 (2003)

Formula: C₂₂H₂₇MnN₄O₁₄P₂·3Na

Purity: >85%

Color and Shape: Neat

Molecular weight: 757.32

Ref: TR-M163700

Mangafodipir trisodium

CAS: 140678-14-4

Mangafodipir trisodium is a contrast agent that is used in nuclear imaging to diagnose various diseases. Mangafodipir trisodium binds to the DNA, which has been shown to be effective at low doses with human serum. The binding of this drug prevents cell lysis and thereby enhances the amount of time that cells are viable for imaging. Mangafodipir trisodium has also been shown to cause liver lesions at high doses, but does not affect the heart or kidneys. It has been found to be toxic in animal studies and should not be administered if there is any sign of kidney failure.

Formula: C₂₂H₂₇MnN₄Na₃O₁₄P₂

Purity: Min. 95%

Molecular weight: 757.32 g/mol

Ref: 3D-QFA67814

Mangafodipir Trisodium (DISCONTINUED)

CAS: 140678-14-4

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₂₂H₂₇MnN₄Na₃O₁₄P₂

Color and Shape: Powder

Molecular weight: 757.00725

Ref: 45-1375069