CAS 140712-80-7

N-Benzoyl-3′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine

Description:

N-Benzoyl-3′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine is a synthetic nucleoside derivative that exhibits unique structural and chemical characteristics. This compound features a deoxycytidine backbone, which is a component of DNA, modified with a benzoyl group and a bis(4-methoxyphenyl)phenylmethyl substituent at the 3′ position. The presence of the benzoyl group enhances its lipophilicity, potentially influencing its ability to penetrate cellular membranes. The methoxy groups on the phenyl rings can contribute to the compound's electronic properties and may affect its interactions with biological targets. This compound is of interest in medicinal chemistry and biochemistry, particularly for its potential applications in antiviral or anticancer therapies, as modifications to nucleosides can enhance their efficacy and selectivity. Its CAS number, 140712-80-7, allows for easy identification in chemical databases, facilitating research and development efforts. Overall, the unique structural features of this compound make it a subject of interest for further investigation in pharmaceutical applications.

Formula: C₃₇H₃₅N₃O₇

InChI: InChI=1S/C37H35N3O7/c1-44-29-17-13-27(14-18-29)37(26-11-7-4-8-12-26,28-15-19-30(45-2)20-16-28)47-31-23-34(46-32(31)24-41)40-22-21-33(39-36(40)43)38-35(42)25-9-5-3-6-10-25/h3-22,31-32,34,41H,23-24H2,1-2H3,(H,38,39,42,43)/t31-,32+,34+/m0/s1

InChI key: InChIKey=PTIHHTLJYOOJIY-VOTWKOMSSA-N

SMILES: C(O[C@@H]1[C@@H](CO)O[C@H](C1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Synonyms:

• Cytidine, N-benzoyl-3′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-
• N-Benzoyl-3′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine

N-Benzoyl-3′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine

CAS: 140712-80-7

Formula: C₃₇H₃₅N₃O₇

Molecular weight: 633.6897

Ref: IN-DA001CQJ

N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine

CAS: 140712-80-7

N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine is a novel nucleoside phosphoramidite with antiviral and anticancer activities. It is synthesized from 2'-deoxycytidine and 4-aminobenzoyl chloride in the presence of tetrazole as a catalyst. The cytidine moiety of N4-benzoyl-2'-deoxy-3'-O-DMT-cytidine is activated by diphosphate, which leads to phosphorylation. This nucleotide has shown potential in inhibiting cancer cell growth and may be used for treatment of leukemia, lymphomas, and myeloma.

Formula: C₃₇H₃₅N₃O₇

Purity: Min. 95%

Molecular weight: 633.69 g/mol

Ref: 3D-NB06922