CAS 140865-85-6

5-Thio-L-fucose

CAS: 140865-85-6

5-Thio-L-fucose is a sugar that is found in a variety of tissues and organs. It has been shown to inhibit the antibody-dependent cellular cytotoxicity (ADCC) by binding to the Fc portion of IgG antibodies, which are used to target and destroy cancer cells. 5-Thio-L-fucose has also been shown to modulate the effector functions of natural killer cells and enhance the glycan profile of dendritic cells. It may be useful as a supplement for patients undergoing chemotherapy or radiation therapy, where it may help inhibit the growth of tumor cells. 5-Thio-L-fucose inhibits ADCC activity by binding to IgG antibodies, preventing them from attaching to immune cells, which would otherwise act as effectors in destroying tumor cells. This inhibition can be reversed with a competitive inhibitor such as D-arabinose.

Formula: C₆H₁₂O₄S

Purity: Min. 95%

Molecular weight: 180.22 g/mol

Ref: 3D-MT61555