CAS 141018-26-0
:1-(6-Amino-2-iodo-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-β-D-ribofuranuronic acid
Description:
1-(6-Amino-2-iodo-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-β-D-ribofuranuronic acid, with CAS number 141018-26-0, is a complex organic compound that features a purine base structure, which is characteristic of nucleobases found in nucleic acids. The presence of an amino group and an iodine atom on the purine ring suggests potential reactivity and biological significance, possibly influencing its role in biochemical pathways. The β-D-ribofuranuronic acid moiety indicates that this compound is a derivative of ribose, which is essential in the structure of nucleotides and nucleic acids. The methylethylidene group introduces steric hindrance, which may affect the compound's conformation and interactions with biological macromolecules. Overall, this compound may exhibit interesting pharmacological properties, making it a candidate for further research in medicinal chemistry and biochemistry, particularly in the context of nucleoside analogs and their applications in antiviral or anticancer therapies.
Formula:C13H14IN5O5
InChI:InChI=1S/C13H14IN5O5/c1-13(2)23-5-6(24-13)10(22-7(5)11(20)21)19-3-16-4-8(15)17-12(14)18-9(4)19/h3,5-7,10H,1-2H3,(H,20,21)(H2,15,17,18)/t5-,6+,7-,10+/m0/s1
InChI key:InChIKey=BPWZMRNNBQGXEV-HEZDBXPZSA-N
SMILES:C(O)(=O)[C@H]1O[C@H]([C@]2([C@@]1(OC(C)(C)O2)[H])[H])N3C=4C(N=C3)=C(N)N=C(I)N4
Synonyms:- Furo[3,4-d]-1,3-dioxole, β-D-ribofuranuronic acid deriv.
- β-D-Ribofuranuronic acid, 1-(6-amino-2-iodo-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-
- 1-(6-Amino-2-iodo-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-β-D-ribofuranuronic acid
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Found 3 products.
β-D-Ribofuranuronic acid, 1-(6-amino-2-iodo-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-
CAS:Formula:C14H16IN5O5Color and Shape:SolidMolecular weight:461.21185'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine
CAS:<p>5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine is an antiviral and anticancer monophosphate nucleoside. It has been shown to be a potent inhibitor of HIV replication in vitro, with IC50 values of 0.5 μM for HIV-1 and 0.8 μM for HIV-2. 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine also inhibits the replication of herpes simplex virus type 1 (IC50 = 0.7 μM) and cytomegalovirus (IC50 = 2.6 μM). 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine was found to be more than 10 times as potent as adenosine in inhibiting DNA synthesis in human tumor cell lines, including leukemia cells, carcinoma cells,</p>Formula:C13H14IN5O5Purity:Min. 95%Molecular weight:447.19 g/mol
