CAS 141018-29-3

2-IODO-5'-ETHYLCARBOXAMIDOADENOSINE

Description:

2-Iodo-5'-ethylcarboxamidoadenosine is a modified nucleoside that belongs to the class of purine derivatives. Its structure features an adenine base linked to a ribose sugar, with an ethylcarboxamide group and an iodine atom at specific positions. This compound is known for its potential biological activity, particularly in the context of cellular signaling and pharmacological applications. The iodine substitution can influence the compound's interaction with biological targets, potentially enhancing its efficacy or altering its metabolic stability. As a nucleoside analog, it may exhibit properties that allow it to interfere with nucleic acid synthesis or function, making it of interest in research related to antiviral or anticancer therapies. Additionally, the presence of the ethylcarboxamide group may affect solubility and bioavailability, which are critical factors in drug development. Overall, 2-Iodo-5'-ethylcarboxamidoadenosine represents a valuable compound for studying nucleoside function and developing therapeutic agents.

Formula: C₁₃H₁₇IN₆O₅

InChI: InChI=1/C12H15IN6O4/c1-2-15-10(22)7-5(20)6(21)11(23-7)19-3-16-4-8(14)17-12(13)18-9(4)19/h3,5-7,11,20-21H,2H2,1H3,(H,15,22)(H2,14,17,18)/t5-,6?,7+,11-/m1/s1

Synonyms:

• 5'-Ethylcarboxamido-2-iodo-D-adenosine
• 1-(6-AMino-2-iodo-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronaMide
• 5'-Ethylcarboxamido-2-iodoadenosine

2-Iodo-5’-ethylcarboxamido Adenosine

CAS: 141018-29-3

Formula: C₁₃H₁₇IN₆O₅

Color and Shape: Solid

Molecular weight: 464.2157

Ref: IN-DA001FQZ

5''-Ethylcarboxamido-2-iodoadenosine

CAS: 141018-29-3

Ref: 7W-GN1512

2-Iodo-5’-ethylcarboxamido Adenosine

Controlled Product

CAS: 141018-29-3

Applications 2-Iodo-5’-ethylcarboxamido Adenosine is a potent and selective adenosine receptor agonist (1,2). 2-Iodo-5’-ethylcarboxamido Adenosine can be used to determine binding and structural properties between receptor subtypes.
References (1) Cristalli, G., et al.: J. Med. Chem. 38, 1462 (1995) (2) Reiger, J. M., et al.: J. Med. Chem., 44, 531 (2001)

Formula: C₁₃H₁₇IN₆O₅

Color and Shape: Neat

Molecular weight: 464.22

Ref: TR-I706000

5'-Ethylcarboxamido-2-iodoadenosine

CAS: 141018-29-3

5'-Ethylcarboxamido-2-iodoadenosine is a novel antiviral drug that belongs to the class of deoxyribonucleosides. It has been shown to inhibit viral replication at the level of DNA synthesis and RNA transcription. 5'-Ethylcarboxamido-2-iodoadenosine has shown activity against cancer cells as well as antiviral activity against HIV and influenza virus. This compound has also been shown to be an activator of phosphoramidites, which are used in many industrial chemical reactions. 5'-Ethylcarboxamido-2-iodoadenosine is synthesized from 2',3'-dideoxyadenosine by replacing the 3' hydroxyl group with ethyl carboxamide group. It is then reacted with iodine to give the final product, 5'-ethylcarboxamido-2-iodoadenosine.

Formula: C₁₂H₁₅IN₆O₄

Purity: Min. 95%

Molecular weight: 434.19 g/mol

Ref: 3D-NE06317

2-Iodo-5-ethylcarboxamido Adenosine

CAS: 141018-29-3

Formula: C₁₂H₁₅IN₆O₄

Molecular weight: 434.19

Ref: ST-EA-CP-A88055