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CAS 14110-64-6

:

cytochalasin A

Description:
Cytochalasin A is a naturally occurring compound classified as a cytochalasins, which are a group of fungal metabolites known for their ability to disrupt cytoskeletal functions. It is primarily derived from the fungus *Helminthosporium* and exhibits a complex structure characterized by a lactone ring and a polycyclic backbone. Cytochalasin A is recognized for its potent ability to inhibit actin polymerization, which affects cell motility, division, and various cellular processes. This compound has been extensively studied in cell biology and pharmacology for its effects on the cytoskeleton, making it a valuable tool in research. Additionally, cytochalasin A has shown potential in various therapeutic applications, including cancer research, due to its ability to induce apoptosis in certain cell types. However, its use is often limited by its cytotoxicity and the need for careful handling in laboratory settings. Overall, cytochalasin A serves as an important compound for understanding cellular dynamics and exploring new therapeutic avenues.
Formula:C29H35NO5
InChI:InChI=1/C29H35NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,23-24,26-27,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15u/t18-,19-,23-,24-,26+,27+,29-/m0/s1
InChI key:InChIKey=ZMAODHOXRBLOQO-TZVKRXPSSA-N
SMILES:O=C1[C@]23[C@]([C@H](CC4=CC=CC=C4)N1)([C@H](C)C(=C)[C@@H](O)[C@@]2(/C=C/C[C@H](C)CCCC(=O)\C=C\C(=O)O3)[H])[H]
Synonyms:
  • (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione
  • (9R,11E,12aS,13S,15R,15aR,16S,18aR)-16-benzyl-13-hydroxy-9,15-dimethyl-14-methylidene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione
  • (9S,11E,12aS,13S,15R,15aR,16S,18aR)-16-benzyl-13-hydroxy-9,15-dimethyl-14-methylidene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione
  • 16-benzyl-13-hydroxy-9,15-dimethyl-14-methylidene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione
  • 24-Oxa(14)cytochalasa-6(12),13,21-triene-1,20,23-trione, 7-hydroxy-16-methyl-10-phenyl-, (7S,13E,16R,21E)-
  • 2H-Oxacyclotetradecino(2,3-d)isoindole-2,5,18-trione, 16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-
  • 2H-Oxacyclotetradecino(2,3-d)isoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-
  • 2H-Oxacyclotetradecino(2,3-d)isoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (9R-(3E,9R*,11E,12aS*,13S*,15S*,15aS*,16S*,18aS*))-
  • 5,5-Didehydrophomin
  • 5-Dehydrophomin
  • See more synonyms
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Found 4 products.
  • Cytochalasin A
    Glentham
    + Info

    Cytochalasin A

    CAS:
    Formula:C29H35NO5
    Molecular weight:477.60

    Ref: 7W-GK1420

    ne
    To inquire
  • Cytochalasin A
    Apollo Scientific
    + Info

    Cytochalasin A

    CAS:
    <p>Cytochalasin A</p>
    Formula:C29H35NO5
    Purity:By hplc: 100% (Typical Value in Batch COA)
    Color and Shape: white powder
    Molecular weight:477.59g/mol

    Ref: 54-BIC1013

    1mg
    106.00€
    5mg
    353.00€
    10mg
    622.00€
    25mg
    1,234.00€
    50mg
    2,221.00€
    100mg
    3,990.00€
  • Cytochalasin A
    Targetmol
    + Info

    Cytochalasin A

    CAS:
    <p>Cytochalasin A, a cell-penetrating fungal toxin, blocks HIV-1 protease (IC50 = 3 μM) and hinders actin and microtubule assembly. It's an antibiotic.</p>
    Formula:C29H35NO5
    Purity:98%
    Color and Shape:White Crystalline Powder
    Molecular weight:477.59

    Ref: TM-T10928

  • Cytochalasin A
    TRC
    + Info

    Cytochalasin A

    CAS:
    <p>Applications Cytochalasin A binds to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Preventing growth and sugar uptake in a Saccharomyces strain.<br>References Griffin, J. et al.: Proc. Natl. Acad. Sci., 79, 3759 (1982);<br></p>
    Formula:C29H35NO5
    Color and Shape:Neat
    Molecular weight:477.59

    Ref: TR-C998670

    1mg
    299.00€