5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a modified nucleoside analog that incorporates a fluorine atom and a bulky trimethylphenyl group into the uridine structure. This compound is characterized by its potential use in antiviral and anticancer therapies, as it can interfere with nucleic acid synthesis. The presence of the fluorine atom enhances its stability and bioactivity, while the bulky trimethylphenyl substituent may influence its interaction with nucleic acid targets and cellular uptake. The compound is typically studied for its effects on DNA and RNA synthesis, as well as its ability to inhibit specific enzymes involved in nucleotide metabolism. Its unique structural features contribute to its pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. As with many nucleoside analogs, the evaluation of its efficacy and safety in biological systems is crucial for understanding its potential therapeutic applications.

5-FLUORO-O4-(2,4,6-TRIMETHYLPHENYL)-2'-DEOXYURIDINE

141120-63-0: 5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a modified nucleoside analog that incorporates a fluorine atom and a bulky trimethylphenyl group into the uridine structure. This compound is characterized by its potential use in antiviral and anticancer therapies, as it can interfere with nucleic acid synthesis. The presence of the fluorine atom enhances its stability and bioactivity, while the bulky trimethylphenyl substituent may influence its interaction with nucleic acid targets and cellular uptake. The compound is typically studied for its effects on DNA and RNA synthesis, as well as its ability to inhibit specific enzymes involved in nucleotide metabolism. Its unique structural features contribute to its pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. As with many nucleoside analogs, the evaluation of its efficacy and safety in biological systems is crucial for understanding its potential therapeutic applications.

<p>5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a novel monophosphate nucleotide activated with 2,4,6-trimethylphenyl (TMP) and used as a building block in the synthesis of oligonucleotides. The synthesized nucleoside can be converted to a diphosphate or phosphoramidite. 5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is an anticancer agent that inhibits DNA synthesis by inhibiting ribonucleic acid (RNA) synthesis. It has been shown to inhibit the proliferation of human leukemia cells and may have potential for use in therapy for cancer treatment.</p>

CAS 141120-63-0

5-FLUORO-O4-(2,4,6-TRIMETHYLPHENYL)-2'-DEOXYURIDINE

5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine

Ref: 3D-RFA12063