CAS 141136-83-6

TRAP-6

Description:

TRAP-6, also known by its CAS number 141136-83-6, is a synthetic peptide that serves as a potent agonist for the thrombin receptor, also known as the protease-activated receptor 1 (PAR-1). This peptide is characterized by its ability to mimic the action of thrombin, a key enzyme in the coagulation cascade, thereby influencing various physiological processes such as platelet activation and vascular permeability. TRAP-6 is often utilized in research to study platelet function and the mechanisms of thrombosis and hemostasis. Its structure typically includes a sequence of amino acids that allows it to effectively bind to and activate PAR-1, leading to downstream signaling pathways that can affect cellular responses. The compound is of interest in pharmacological studies, particularly in the context of cardiovascular diseases and potential therapeutic interventions. As with many peptides, its stability, solubility, and bioavailability are important factors that influence its application in both in vitro and in vivo studies.

Formula: C₃₄H₅₆N₁₀O₉

TRAP-6

CAS: 141136-83-6

SFLLRN corresponds to residues 42-47 of the thrombin receptor. The hexapeptide acts as a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 µM and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca²⁺.

Formula: C₃₄H₅₆N₁₀O₉

Purity: 98.4%

Color and Shape: White Lyophilisate

Molecular weight: 748.88

Ref: 01-4017752

L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine

CAS: 141136-83-6

Formula: C₃₄H₅₆N₁₀O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 748.8700

Ref: IN-DA003AP5

Thrombin Receptor Activator Peptide 6

CAS: 141136-83-6

Formula: C₃₄H₅₆N₁₀O₉

Purity: ≥ 95.0%

Color and Shape: White to beige powder

Molecular weight: 748.90

Ref: 7W-GK7137

Thrombin Receptor Activator Peptide 6

CAS: 141136-83-6

Thrombin Receptor Activator Peptide 6

Formula: C₃₄H₅₆N₁₀O₉

Purity: By hplc: 98.4% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 748.87g/mol

Ref: 54-BIBA1005

TRAP-6

CAS: 141136-83-6

TRAP-6

Purity: ≥98%

Molecular weight: 748.87g/mol

Ref: 54-BUP02503

TRAP-6

CAS: 141136-83-6

TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).

Formula: C₃₄H₅₆N₁₀O₉

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 748.87

Ref: TM-T7625

H-Ser-Phe-Leu-Leu-Arg-Asn-OH

CAS: 141136-83-6

H-Ser-Phe-Leu-Leu-Arg-Asn-OH is a biocompatible polymer that has been shown to have strong antioxidative properties. This polymer has been used in the development of a new class of drug for the treatment of inflammatory bowel disease, which may be due to its ability to inhibit toll-like receptor activity. H-Ser-Phe-Leu-Leu-Arg-Asn-OH also has potent immunosuppressive and antiinflammatory activities, and is stable at doses up to 200mg/kg. These properties make this polymer an attractive candidate for use as a therapeutic agent in treating bowel disease.

Formula: C₃₄H₅₆N₁₀O₉

Purity: Min. 95%

Molecular weight: 748.87 g/mol

Ref: 3D-PAR-3943-PI

H-Ser-Phe-Leu-Leu-Arg-Asn-OH

CAS: 141136-83-6

Purity: ≥96%

Molecular weight: 748.423

Ref: 10-F862560

TRAP-6 ammonium acetate salt

CAS: 141136-83-6

TRAP-6 is a biocompatible polymer that is used to prevent adhesion of platelets to the endothelium and activation of coagulation. TRAP-6 has been shown to be effective in preventing inflammatory bowel disease, as well as other bowel diseases, by inhibiting the release of inflammatory cytokines such as fibrinogen and erythropoietin. This drug has been shown to have clinical relevance in treating inflammatory bowel disease in animal models. TRAP-6 can also be used to inhibit the growth of bacteria by binding to bacterial cells or by inducing their death. In addition, TRAP-6 can bind with monoclonal antibodies and target specific cells for destruction.

Formula: C₃₄H₅₆N₁₀O₉

Purity: Min. 95%

Molecular weight: 748.87 g/mol

Ref: 3D-FT110252