Description:TRAP-6, also known by its CAS number 141136-83-6, is a synthetic peptide that serves as a potent agonist for the thrombin receptor, also known as the protease-activated receptor 1 (PAR-1). This peptide is characterized by its ability to mimic the action of thrombin, a key enzyme in the coagulation cascade, thereby influencing various physiological processes such as platelet activation and vascular permeability. TRAP-6 is often utilized in research to study platelet function and the mechanisms of thrombosis and hemostasis. Its structure typically includes a sequence of amino acids that allows it to effectively bind to and activate PAR-1, leading to downstream signaling pathways that can affect cellular responses. The compound is of interest in pharmacological studies, particularly in the context of cardiovascular diseases and potential therapeutic interventions. As with many peptides, its stability, solubility, and bioavailability are important factors that influence its application in both in vitro and in vivo studies.
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