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CAS 141176-92-3

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α1-Antichymotrypsin

Description:
α1-Antichymotrypsin (ACT) is a serine protease inhibitor primarily produced in the liver, playing a crucial role in regulating proteolytic enzymes in the body. It belongs to the serpin family, which is characterized by a unique structure that allows it to inhibit various proteases, particularly those involved in inflammation and tissue remodeling. ACT is known for its ability to inhibit chymotrypsin and other serine proteases, thereby modulating inflammatory responses and protecting tissues from damage. The protein is glycosylated, which affects its stability and activity. In clinical contexts, altered levels of α1-antichymotrypsin have been associated with various diseases, including chronic obstructive pulmonary disease (COPD) and certain cancers, making it a potential biomarker for these conditions. Additionally, its role in the inflammatory process highlights its importance in both physiological and pathological states. Overall, α1-antichymotrypsin is a vital component of the body's defense mechanisms, contributing to the balance of proteolytic activity and inflammation.
Formula:Unspecified
Synonyms:
  • Aact, Human
  • Alpha-1-X
  • Alpha-1-X-Glycoprotein
  • Alpha-1X-Glycoprotein, Human
  • Anti-Aact, Human
  • Anti-Antichymotrypsin, Alpha-1-, Human
  • Antichymotrypsin, Alpha-1, Human
  • Chymotrypsin inhibitor, α<sub>1</sub>-
  • Proteins, AACT
  • Serpin A 3
  • See more synonyms
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