CAS 141223-71-4

N-cbz-val-lys-met 7-amido-4-*methylcoumarin

Description:

N-Cbz-val-lys-met 7-amido-4-methylcoumarin is a synthetic compound that belongs to the class of peptide derivatives, characterized by the presence of a carbobenzyloxy (Cbz) protecting group on the valine residue and a 7-amido-4-methylcoumarin moiety, which is often used as a fluorescent marker in biochemical applications. This compound typically exhibits properties such as solubility in organic solvents and moderate stability under physiological conditions, making it suitable for various biochemical assays. The presence of the coumarin group imparts fluorescence, allowing for detection and quantification in biological systems. Additionally, the peptide structure suggests potential bioactivity, including interactions with enzymes or receptors, which can be explored in drug development or molecular biology studies. Its specific applications may include use as a substrate in enzyme assays or as a probe in cellular imaging. As with many peptide derivatives, careful handling and storage conditions are recommended to maintain its integrity and functionality.

Formula: C₃₄H₄₅N₅O₇S

Synonyms:

• Z-Val-Lys-Met-AMC

Z-Val-Lys-Met-AMC

CAS: 141223-71-4

The motif VKM corresponds to APP (669-671). Substrate for Amyloid A4-generating enzymes and cathepsin B. Hook et al. used Z-VKM-MCA to detect β-secretase activity in isolated chromaffin vesicles.

Formula: C₃₄H₄₅N₅O₇S

Purity: > 98%

Color and Shape: White Lyophilisate

Molecular weight: 667.83

Ref: 01-4017732

L-Methioninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

CAS: 141223-71-4

Formula: C₃₄H₄₅N₅O₇S

Molecular weight: 667.8154

Ref: IN-DA001G3H

Z-Val-Lys-Met-MCA

CAS: 141223-71-4

Z-Val-Lys-Met-MCA is a synthetic peptide that can act as an inhibitor or activator. Z-Val-Lys-Met-MCA binds to the receptor and inhibits the receptor from binding with its ligand, which prevents activation of the receptor. It also has been shown to activate other receptors, such as ion channels, by binding to them. This makes it an important research tool for understanding protein interactions.

Formula: C₃₄H₄₅N₅O₇S

Purity: Min. 95%

Molecular weight: 667.82 g/mol

Ref: 3D-MVM-3156-V

Z-Val-Lys-Met-AMC acetate salt

CAS: 141223-71-4

Bortezomib is a proteasome inhibitor that binds to the catalytic site of the proteasome and inhibits its activity. Bortezomib is used as an anticancer agent to treat multiple myeloma, T-cell lymphomas, and other cancers. It has been shown to inhibit the growth of cancer cells and slow tumor progression in animal models. The drug has also been shown to decrease insulin resistance in mice with high blood sugar levels by inhibiting histone deacetylase (HDAC). This inhibition leads to increased expression of genes that are involved in glucose metabolism and decreased expression of genes that regulate fat production.
The drug also binds tightly to the insulin receptor, which may lead to improved glucose uptake into cells.

Formula: C₃₄H₄₅N₅O₇S

Purity: Min. 95%

Molecular weight: 667.82 g/mol

Ref: 3D-FV110562