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CAS 141294-77-1

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C-type natriuretic peptide-53 human

Description:
C-type natriuretic peptide (CNP) is a member of the natriuretic peptide family, which plays a crucial role in cardiovascular homeostasis. The human form of CNP, specifically C-type natriuretic peptide-53, is a 53-amino acid peptide that is primarily produced in the brain and vascular endothelium. It is involved in various physiological processes, including vasodilation, inhibition of smooth muscle proliferation, and regulation of blood pressure. CNP exerts its effects by binding to specific receptors, leading to the activation of guanylate cyclase and subsequent increase in intracellular cyclic GMP levels. This signaling pathway contributes to its role in promoting vascular relaxation and inhibiting the renin-angiotensin-aldosterone system. The peptide is also implicated in bone growth and development. Due to its physiological significance, CNP and its analogs are being explored for therapeutic applications in conditions such as heart failure and hypertension. The CAS number 141294-77-1 uniquely identifies this specific peptide in chemical databases, facilitating research and development in pharmacology and biochemistry.
Formula:C251H417N81O71S3
Synonyms:
  • C-Type Natriuretic Peptide (1-53) (human)
  • H-Asp-Leu-Arg-Val-Asp-Thr-Lys-Ser-Arg-Ala-Ala-Trp-Ala-Arg-Leu-Leu-Gln-Glu-His-Pro-Asn-Ala-Arg-Lys-Tyr-Lys-Gly-Ala-Asn-Lys-Lys-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-OH (Disulfide bond)
  • Cnp-53 (Human)
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