CAS 141368-69-6

H-GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH

Description:

The chemical substance identified as H-GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH, with the CAS number 141368-69-6, is a peptide composed of a sequence of amino acids. This peptide features a combination of hydrophobic and polar side chains, which contribute to its structural and functional properties. The presence of glycine (GLY), isoleucine (ILE), leucine (LEU), phenylalanine (PHE), valine (VAL), and threonine (THR) suggests that it may exhibit characteristics typical of peptides, such as potential biological activity, including hormone-like or neurotransmitter functions. The terminal hydroxyl group (-OH) indicates that it is likely a peptide with a free carboxyl group, which can influence its solubility and reactivity. Peptides like this one are often studied for their roles in biological systems, including signaling pathways and metabolic processes. Additionally, their stability, interaction with receptors, and potential therapeutic applications are of significant interest in biochemistry and pharmacology.

Formula: C₄₉H₇₅N₉O₁₁

Synonyms:

• Matrix Protein M1 (58-66) (Influenza A Virus)
• H2N-Gilgfvftl-Oh
• Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu
• Influenza Matrix Peptide
• Influenza Matrix Protein M1 (58-66)
• Influenza Virus Matrix Protein (58-66)
• Gilgfvftl

Matrix Protein M1 (58-66) (Influenza A virus)

CAS: 141368-69-6

Bachem ID: 4095875.

Formula: C₄₉H₇₅N₉O₁₁

Purity: 96.8%

Color and Shape: White Lyophilisate

Molecular weight: 966.19

Ref: 01-4095875

CEF1, Influenza Matrix Protein M1 (58-66)

CAS: 141368-69-6

CEF1, M1 (58-66) epitope from influenza A; GILGFVFTL is HLA-A2-restricted.

Formula: C₄₉H₇₅N₉O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 966.17

Ref: TM-TP1717

Flu mp 58

CAS: 141368-69-6

Portion of Influenza M

Formula: C₄₉H₇₅N₉O₁₁

Color and Shape: Powder

Molecular weight: 966.18 g/mol

Ref: 3D-CRB1001165

Matrix Protein M1 (58-66) (Influenza A virus) acetate salt

CAS: 141368-69-6

Please enquire for more information about Matrix Protein M1 (58-66) (Influenza A virus) acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₄₉H₇₅N₉O₁₁

Purity: Min. 95%

Molecular weight: 966.17 g/mol

Ref: 3D-FM109635

H-GILGFVFTL-OH

CAS: 141368-69-6

FluM1 (58-66) is a short part of the matrix protein of Influenza A virus which is the most abundant component of this enveloped virus localized under the viral lipid envelope. The GILGFVFTL epitope is highly conserved in Influenza A virus strains at a rate of 93% for 69 strains tested. Human Influenza epitopes may bind MHC molecules and then may be recognized by CD8+ cytotoxic T cells. Applications of FluM1 (58-66): FluM1 (58-66) is used to stimulate CTL responses in peripheral blood mononuclear cells (PBMCs). Then, ELISPOT assay is used to quantify peptide epitope specificity and IFN-γ releasing effector cells. FluM1 (58-66) has shown CTL responses qualified of immunodominant with restriction by HLA-A*02:01. It has also been detected CTL responses when FluM1 (58-66) is restricted by all HLA-C. Therefore, FluM1 (58-66) may help to understand the reaction of immune system against Influenza virus of each populations having different HLA type. FluM1 (58-66) has indeed prompted research to develop T-cell vaccine strategies capable of inducing specific CTL responses in patients upon immunization with Influenza M1 antigenic epitope. MVA-NP+M1 vaccine use GILGFVFTL epitope and is tested in clinical trial. Potential cross-reactivity with HIV-1 p17 Gag (77-85): Moreover, FluM1 (58-66) share similarities with HIV-1 p17 Gag (77-85) which can potentially show a cross-reactivity between these epitopes. It has been demonstrated a cross-reactivity and results suggest that immunity following infection by Influenza virus causes specific immune response to HIV-1 p17 Gag (77-85).

Formula: C₄₉H₇₅N₉O₁₁

Molecular weight: 966.18 g/mol

Ref: 3D-PP48052