CAS 141374-81-4

Tarazepide

Description:

Tarazepide, with the CAS number 141374-81-4, is a chemical compound that functions primarily as a selective antagonist of the neurokinin-1 (NK1) receptor. This receptor is involved in various physiological processes, including pain perception, stress response, and the regulation of mood. Tarazepide's structure features a unique arrangement of functional groups that contribute to its biological activity. It has been studied for its potential therapeutic applications, particularly in the treatment of conditions related to anxiety and depression, as well as in the modulation of pain pathways. The compound exhibits moderate solubility in organic solvents, which is typical for many pharmacologically active substances. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile in clinical settings. Overall, Tarazepide represents a significant interest in medicinal chemistry due to its targeted action on neurokinin receptors, offering insights into the development of new therapeutic agents for neuropsychiatric disorders.

Formula: C₂₈H₂₄N₄O₂

InChI: InChI=1/C28H24N4O2/c1-31-22-15-6-5-14-21(22)24(18-9-3-2-4-10-18)29-26(28(31)34)30-27(33)23-17-20-12-7-11-19-13-8-16-32(23)25(19)20/h2-7,9-12,14-15,17,26H,8,13,16H2,1H3,(H,30,33)/t26-/m1/s1

SMILES: CN1c2ccccc2C(=N[C@@H](C1=O)N=C(c1cc2cccc3CCCn1c23)O)c1ccccc1

Synonyms:

• Tarazepide [INN]
• (-)-N-((S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-5,6-dihydro-4H-pyrrolo(3,2,1-ij)quinoline-2-carboxamide
• Unii-Rk2972Yz2U
• N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxamide
• N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxamide

Tarazepide

CAS: 141374-81-4

Tarazepide is a peptide that binds to potassium channels and regulates their activity. It has been studied in an effort to understand the ion channel function of the brain, but it has also been used as a research tool. Tarazepide is synthesized by solid-phase peptide synthesis and purified by HPLC. The purity of this product exceeds 98%.

Formula: C₂₈H₂₄N₄O₂

Purity: Min. 95%

Molecular weight: 448.5 g/mol

Ref: 3D-RFA37481

Tarazepide

CAS: 141374-81-4

Tarazepide is a potent and specific antagonist of CCK-A receptor.

Formula: C₂₈H₂₄N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 448.52

Ref: TM-T13084