CAS 1414-45-5

nisin from streptococcus lactis

Description:

Nisin is a polycyclic antibacterial peptide produced by the bacterium Lactococcus lactis, specifically classified as a lantibiotic due to its unique structure that includes unusual amino acids. It is characterized by its ability to inhibit the growth of a wide range of Gram-positive bacteria, including some pathogens, making it a valuable preservative in the food industry. Nisin functions by binding to lipid II, a key component in bacterial cell wall synthesis, disrupting the cell membrane and ultimately leading to cell death. It is recognized for its heat stability and effectiveness at low concentrations, which contributes to its use in food preservation, particularly in dairy products and canned foods. Additionally, nisin has been studied for its potential applications in medicine, particularly in combating antibiotic-resistant bacteria. Its safety for human consumption has been established, and it is classified as a Generally Recognized As Safe (GRAS) substance by regulatory agencies. Overall, nisin is a significant biopreservative with both industrial and potential therapeutic applications.

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

InChI: InChI=1/C143H230N42O37S7/c1-24-69(11)105(148)135(213)162-82(27-4)118(196)174-94-58-225-59-95(175-123(201)89(48-67(7)8)169-115(193)74(16)158-138(216)107(70(12)25-2)180-132(94)210)133(211)184-112-79(21)229-61-96(160-104(190)56-152-134(212)100-38-34-44-185(100)142(112)220)128(206)164-84(36-29-32-42-145)120(198)182-109-76(18)226-60-97(161-103(189)55-151-117(195)85(39-45-223-22)165-122(200)88(47-66(5)6)168-113(191)72(14)156-102(188)54-153-136(109)214)129(207)171-92(51-101(147)187)125(203)166-86(40-46-224-23)119(197)163-83(35-28-31-41-144)121(199)183-110-77(19)228-63-99-130(208)170-90(49-80-52-149-64-154-80)124(202)176-98(62-227-78(20)111(141(219)177-99)181-116(194)75(17)159-140(110)218)131(209)173-93(57-186)127(205)179-108(71(13)26-3)139(217)172-91(50-81-53-150-65-155-81)126(204)178-106(68(9)10)137(215)157-73(15)114(192)167-87(143(221)222)37-30-33-43-146/h27,52-53,64-72,75-79,83-100,105-112,186H,15-16,24-26,28-51,54-63,144-146,148H2,1-14,17-23H3,(H2,147,187)(H,149,154)(H,150,155)(H,151,195)(H,152,212)(H,153,214)(H,156,188)(H,157,215)(H,158,216)(H,159,218)(H,160,190)(H,161,189)(H,162,213)(H,163,197)(H,164,206)(H,165,200)(H,166,203)(H,167,192)(H,168,191)(H,169,193)(H,170,208)(H,171,207)(H,172,217)(H,173,209)(H,174,196)(H,175,201)(H,176,202)(H,177,219)(H,178,204)(H,179,205)(H,180,210)(H,181,194)(H,182,198)(H,183,199)(H,184,211)(H,221,222)/b82-27+/t69-,70-,71-,72-,75?,76?,77?,78?,79?,83-,84+,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,105-,106-,107-,108-,109+,110-,111-,112-/m0/s1

Synonyms:

• Nisin
• Ambicin N
• Delvoplus
• E 234
• L-Lysine, L-isoleucyl-(Z)-2,3-didehydro-2-aminobutanoyl-D-cysteinyl-L-isoleucyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-threo-3-mercapto-D-2-aminobutanoyl-L-prolylglycyl-L-cysteinyl-L-lysyl-threo-3-mercapto-D-2-aminobutanoylglycyl-L-alanyl-L-leucyl-L-methionylglycyl-L-cysteinyl-L-asparaginyl-L-methionyl-L-lysyl-threo-3-mercapto-D-2-aminobutanoyl-L-alanyl-threo-3-mercapto-D-2-aminobutanoyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-seryl-L-isoleucyl-L-histidyl-L-valyl-2,3-didehydroalanyl-, cyclic (3→7),(8→11),(13→19),(23→26),(25→28)-pentakis(sulfide)
• MicroGARD MG 300
• Nisaplin
• Nisin A
• Nisin(1-34)
• Nisina
• Nisine
• Nisitrol

Nisin, 900 I.U./mg

CAS: 1414-45-5

Nisin, 1414-45-5, is a polypeptide produced by Lactococcus lactis which has antibacterial properties and can be used as a selection agent in cell culture applications. Learn more.

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

Color and Shape: Pale cream to pale brown, Powder

Molecular weight: 3354.09

Ref: 02-J66370

nisin from streptococcus lactis

CAS: 1414-45-5

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

Color and Shape: Solid

Molecular weight: 3354.0705

Ref: IN-DA003T4A

Nisin

CAS: 1414-45-5

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

Purity: ≥ 900IU/mg (as is)

Color and Shape: Off-white to light-brown powder

Molecular weight: 3354.07

Ref: 7W-GA1106

Nisin

CAS: 1414-45-5

Nisin

Molecular weight: 3,354.12g/mol

Ref: 54-BI9880

Nisin RS

CAS: 1414-45-5, 7647-14-5

Color and Shape: White To Pale Yellow-Red Solid Powder

Ref: 2K-5014000021

Nisin A, Technical grade (~2.5% mainly sodium chloride and denatured milk solids)

CAS: 1414-45-5

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

Color and Shape: White To Light Brown

Molecular weight: 3354.07

Ref: TR-N487550

Nisin

CAS: 1414-45-5

Nisin A: a lantibiotic peptide made by L. lactis, contains unique amino acids like lanthionine, and fights bacteria.

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 3354.07

Ref: TM-TP1329

Nisin - >900IU/mg, contains min 50% NaCl

CAS: 1414-45-5

Nisin (>900 IU/mg, contains min 50% NaCl) is a lantibiotic peptide with action on bacterial cell membranes and is used for preserving food and controlling gram-positive bacteria.

Formula: C₁₄₃H₂₃₀N₄₂O₃₇S₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 3,354.08 g/mol

Ref: 3D-FN38985