CAS 141430-65-1

N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide

Description:

N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide, with CAS number 141430-65-1, is a chemical compound characterized by its complex structure, which includes a sulfonamide group, a methoxy group, and an amino group attached to a pyridine ring. This compound typically exhibits properties associated with sulfonamides, such as potential antibacterial activity, although its specific biological activity may vary. The presence of the hydroxyphenyl and pyridinyl moieties suggests that it may engage in hydrogen bonding and π-π interactions, which can influence its solubility and reactivity. The methoxy group can enhance lipophilicity, potentially affecting its pharmacokinetic properties. In terms of stability, sulfonamides are generally stable under standard conditions but can be sensitive to strong acids or bases. This compound may be of interest in medicinal chemistry for its potential therapeutic applications, particularly in the development of drugs targeting specific biological pathways. As with all chemical substances, proper handling and safety precautions should be observed due to potential toxicity or reactivity.

Formula: C₁₈H₁₇N₃O₄S

InChI: InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20)

InChI key: InChIKey=URCVCIZFVQDVPM-UHFFFAOYSA-N

SMILES: N(C1=C(NS(=O)(=O)C2=CC=C(OC)C=C2)C=CC=N1)C3=CC=C(O)C=C3

Synonyms:

• Abt 51
• Abt-751
• Benzenesulfonamide, N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-
• E 7010 (pharmaceutical)
• E-7010
• N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide
• N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide
• N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzenesulfonamide

ABT-751

CAS: 141430-65-1

Formula: C₁₈H₁₇N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 371.4103

Ref: IN-DA006YB9

N-(2-((4-Hydroxyphenyl)Amino)Pyridin-3-Yl)-4-Methoxybenzenesulfonamide

CAS: 141430-65-1

N-(2-((4-Hydroxyphenyl)Amino)Pyridin-3-Yl)-4-Methoxybenzenesulfonamide

Purity: 98%

Molecular weight: 371.41g/mol

Ref: 54-OR1023172

ABT-751

CAS: 141430-65-1

ABT-751

Purity: ≥98%

Molecular weight: 371.41g/mol

Ref: 54-BUP06032

ABT-751

CAS: 141430-65-1

Formula: C₁₈H₁₇N₃O₄S

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 371.41

Ref: 3B-A3169

ABT-751

CAS: 141430-65-1

ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.

Formula: C₁₈H₁₇N₃O₄S

Purity: 98.84% - 99.50%

Color and Shape: Solid

Molecular weight: 371.41

Ref: TM-T1758

ABT-751

CAS: 141430-65-1

ABT-751 is a novel, potent, and selective inhibitor of autophagy. It has been shown to induce mitochondrial membrane depolarization and autophagy in HL-60 cells. The drug has also been shown to be effective against cancer cells in vitro, with significant cytotoxicity. In a mouse tumor model, the drug inhibited tumor growth without affecting normal tissues. ABT-751 has also been shown to decrease the levels of epidermal growth factor (EGF) in renal cell cancer cells. The drug is currently undergoing clinical trials for the treatment of cancer patients who are on active antiretroviral therapy and for patients with tumors that are resistant to standard chemotherapy treatments.END>

Formula: C₁₈H₁₇N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 371.41 g/mol

Ref: 3D-RFA43065