
CAS 141467-20-1
:Wee1, gst tagged human
CAS:Wee1 is a cell factor that plays an important role in the regulation of transcription. Wee1 is involved in the regulation of p21, which is a tumor suppressor gene that inhibits cell proliferation. Wee1 may be involved in cancer and stem cell production. Studies have shown that Wee1 is expressed at high levels in women and has been shown to regulate genes that are important for female fertility. Wee1 interacts with factors such as p21 and transcriptional regulators to control the expression of genes related to the immune response, inflammation, and angiogenesis. The expression of Wee1 has also been shown to be regulated by HIF-1α, which plays a key role in tumorigenesis and cellular apoptosis. The inhibition of Wee1 can inhibit endothelial cell proliferation through the inhibition of GSK3β phosphorylation, which results in increased levels of cyclin D2 (CCND2) protein.
Purity:Min. 95%
