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CAS 1414976-20-7

:

Vazegepant HCl

Description:
Vazegepant HCl is a novel small molecule that acts as a selective antagonist of the calcitonin gene-related peptide (CGRP) receptor, which plays a significant role in the pathophysiology of migraine. This compound is characterized by its ability to inhibit CGRP signaling, thereby providing a mechanism for the acute treatment of migraine attacks. Vazegepant is typically administered in its hydrochloride salt form, enhancing its solubility and stability. The substance has been studied for its efficacy in reducing migraine frequency and severity, with a favorable safety profile. Its pharmacokinetic properties include rapid absorption and a relatively short half-life, making it suitable for acute migraine management. As a synthetic compound, Vazegepant HCl is subject to rigorous quality control and regulatory standards to ensure its purity and effectiveness. Overall, its targeted action on the CGRP pathway represents a significant advancement in migraine therapeutics, offering an alternative to traditional treatments.
Formula:C36H47ClN8O3
Synonyms:
  • gepant,CGRP Receptor,Zavegepant,Calcitonin gene-related peptide receptor,receptor,COVID-19,BHV3500,BHV-3500,BHV 3500,Vazegepant,inhibit,inflammation,migraine,intranasal,Inhibitor,Vazegepant hydrochloride,CGRP,soluble
  • Vazegepant hydrochloride
  • Vazegepant HCl salt
  • Vazegepant HCl
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Found 4 products.
  • Vazegepant hydrochloride

    CAS:
    <p>Vazegepant hydrochloride</p>
    Purity:≥98%
    Molecular weight:675.3g/mol

    Ref: 54-BUP02968

    1mg
    165.00€
    5mg
    329.00€
    10mg
    476.00€
    25mg
    791.00€
    50mg
    1,107.00€
    100mg
    1,410.00€
  • Zavegepant HCl

    CAS:
    Formula:C36H46N8O3·HCl
    Molecular weight:638.82 36.46

    Ref: 4Z-Z-046001

    5mg
    To inquire
    10mg
    508.00€
    25mg
    825.00€
    50mg
    1,153.00€
    100mg
    To inquire
  • Vazegepant hydrochloride

    CAS:
    <p>Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.</p>
    Formula:C36H47ClN8O3
    Purity:98.93%
    Color and Shape:Solid
    Molecular weight:675.3
  • Zavegepant Hydrochloride

    Controlled Product
    CAS:
    Formula:C36H46N8O3·HCl
    Color and Shape:Neat

    Ref: TR-Z252510

    50mg
    7,057.00€