CAS 1415-73-2

Barbaloin

Description:

Barbaloin, with the CAS number 1415-73-2, is a naturally occurring compound classified as an anthraquinone glycoside. It is primarily derived from the aloe plant, particularly Aloe vera and Aloe barbadensis. Barbaloin is known for its yellow crystalline appearance and has a molecular formula that reflects its complex structure. This compound exhibits various biological activities, including laxative effects, which are attributed to its ability to stimulate intestinal peristalsis. Additionally, barbaloin has been studied for its potential antioxidant and anti-inflammatory properties. It is soluble in organic solvents but has limited solubility in water. Due to its medicinal properties, barbaloin is often utilized in herbal remedies and cosmetic formulations. However, its use should be approached with caution, as excessive consumption can lead to adverse effects. Overall, barbaloin is a significant compound in both traditional and modern medicine, highlighting the importance of natural products in therapeutic applications.

Formula: C₂₁H₂₂O₉

InChI: InChI=1S/C21H22O9/c22-6-8-4-10-14(21-20(29)19(28)17(26)13(7-23)30-21)9-2-1-3-11(24)15(9)18(27)16(10)12(25)5-8/h1-5,13-14,17,19-26,28-29H,6-7H2/t13-,14+,17-,19+,20-,21+/m1/s1

InChI key: InChIKey=AFHJQYHRLPMKHU-OSYMLPPYSA-N

SMILES: O[C@H]1[C@]([C@@]2(C=3C(C(=O)C=4C2=CC=CC4O)=C(O)C=C(CO)C3)[H])(O[C@H](CO)[C@@H](O)[C@@H]1O)[H]

Synonyms:

• (10R)-1,8-Dihydroxy-3-(hydroxymethyl)-10-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-10H-anthracen-9-one
• (10R)-1,8-dihydroxy-3-(hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]-10H-anthracen-9-one
• (10S)-10-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• (1S)-1,5-anhydro-1-[(9R)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl]-D-glucitol
• 1,5-Anhydro-1-[4,5-Dihydroxy-2-(Hydroxymethyl)-10-Oxo-9,10-Dihydroanthracen-9-Yl]Hexitol
• 1,8-Dihydroxy-10-(beta-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone
• 1,8-dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]-10H-anthracen-9-one
• 10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• 10-beta-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• 10-epi-Aloin B
• 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl beta-D-glucopyranoside
• 9(10H)-Anthracenone, 10-β-<span class="text-smallcaps">D</span>-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (10S)-
• 9(10H)-Anthracenone, 10-β-<span class="text-smallcaps">D</span>-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (S)-
• Aloin A
• Anthrone, 10-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-
• Barbaloin
• Barbaloin A
• Barbaloin From Aloe Barbadensis*Miller Leaves
• NSC 407305
• (10S)-10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (10S)-

Aloin

CAS: 1415-73-2

Aloe exudant, used as a stimulant-laxative

Formula: C₂₁H₂₂O₉

Color and Shape: Yellow, Powder

Molecular weight: 418.40

Ref: 02-J62153

Aloin A

CAS: 1415-73-2

Aloin A analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₂O₉

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 418.4

Ref: 11-0458S

Aloin A ((S)-10-β-D-Glucopyranosyl-1,8-dihydroxy-3-hydroxymethylanthracen-9(10H)-one)

CAS: 1415-73-2

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₂₁H₂₂O₉

Color and Shape: Light Yellow Powder

Molecular weight: 418.12638

Ref: 45-1013727

9(10H)-Anthracenone, 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (10S)-

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Purity: 95%

Color and Shape: Solid

Molecular weight: 418.3940

Ref: IN-DA001GID

(S)-1,8-Dihydroxy-3-(Hydroxymethyl)-10-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Anthracen-9(10H)-One

CAS: 1415-73-2

(S)-1,8-Dihydroxy-3-(Hydroxymethyl)-10-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Anthracen-9(10H)-One

Purity: 95%

Molecular weight: 418.39g/mol

Ref: 54-OR1028303

Aloin A

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Color and Shape: Yellow Solid

Molecular weight: 418.40

Ref: 4Z-A-254002

Aloin

CAS: 1415-73-2

Aloin

Purity: ≥98%

Molecular weight: 418.39g/mol

Ref: 54-BUP14676

Aloin A, 97%

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Purity: ≥ 97.0%

Color and Shape: Pale yellow, beige or dark yellow powder

Molecular weight: 418.40

Ref: 7W-GC6065

Aloin A

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Purity: 95%~99%

Molecular weight: 418.398

Ref: BP-BP0149

Aloin

Controlled Product

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Color and Shape: Neat

Molecular weight: 418.39

Ref: 86-MM1318.01

Aloin

CAS: 1415-73-2

Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.

Formula: C₂₁H₂₂O₉

Purity: 98.28%

Color and Shape: Yellow Powder

Molecular weight: 418.39

Ref: TM-T2742

Aloin

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Color and Shape: Yellow, yellow-green or brown powder

Molecular weight: 418.40

Ref: 7W-GC9451

Aloin a

CAS: 1415-73-2

Natural glycoside

Formula: C₂₁H₂₂O₉

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 418.4

Ref: 5G-89558

Aloin

CAS: 1415-73-2

Formula: C₂₁H₂₂O₉

Molecular weight: 418.4

Ref: ST-EA-CP-D19012

Aloin A

CAS: 1415-73-2

Stability unstable in solution (epimerization)
Applications Aloin is a naturally occurring substance found in various Aloe plant species. Aloin was originally used as a laxative in the treatment of constipation. Recent studies have investigated Aloin as an antineoplastic agent that enhances melanogenesis and transglutaminase activity.
References Farooqi, A.H.A., et al.: J. Med. Aro. Plant. Sci., 31, 159 (2009); Ravi, S., et al: J. Exp. Sci., 2, 10 (2011); Hazrati, S., et al.: J. Med. Plants. Res., 6, 1834 (2012);

Formula: C₂₁H₂₂O₉

Color and Shape: Light Yellow

Molecular weight: 418.39

Ref: TR-A575415

Aloin, mixture of Aloin A and Aloin B

CAS: 1415-73-2

Aloin is a natural bioactive compound, which is a mixture of two diastereomeric compounds: Aloin A and Aloin B. This substance is derived from the latex of the Aloe plant, primarily Aloe vera and Aloe ferox. Aloin functions by irritating the mucosa of the colon, promoting an increase in peristaltic activity. This enhanced colonic movement facilitates bowel movements, making Aloin a potent anthraquinone laxative.

Formula: C₂₁H₂₂O₉

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 418.39 g/mol

Ref: 3D-MA05054

Aloin A

CAS: 1415-73-2

Aloin A is a natural anthraquinone glycoside compound, which is derived from the latex of Aloe species plants, particularly Aloe vera. This compound exhibits its mode of action primarily through the modulation of enzymatic pathways and cellular receptors, ultimately influencing various biological processes. Aloin A operates by interacting with the gastrointestinal tract, where it impacts bowel motility and fluid secretion, exerting its potent laxative effects.

Formula: C₂₁H₂₂O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 418.39 g/mol

Ref: 3D-MA76226