CAS 1415390-47-4

(R)-BPO-27

CAS: 1415390-47-4

Formula: C₂₆H₁₈BrN₃O₆

Purity: 98%

Molecular weight: 548.3416

Ref: IN-DA01EOIN

(R)-BPO-27

CAS: 1415390-47-4

(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.

Formula: C₂₆H₁₈BrN₃O₆

Purity: 99.1%

Color and Shape: Solid

Molecular weight: 548.34

Ref: TM-T10591L

(R)-BPO-27

CAS: 1415390-47-4

(R)-BPO-27 is a membrane permeabilization agent that belongs to the class of enantiomers. It is an enantiomer of butylated hydroxytoluene (BHT), which is a chemical compound used as a food preservative, antioxidant, and stabilizer. The intestinal epithelium cells are the most sensitive target for (R)-BPO-27 with a concentration of 10 μM in vitro. The precise mechanism by which (R)-BPO-27 induces membrane permeabilization is not yet known, but it may be related to inhibition of chloride channels and tyrosine kinase activity in the cell membrane. This drug has been shown to inhibit colon cancer cell growth in vitro and in vivo models.

Formula: C₂₆H₁₈BrN₃O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 548.34 g/mol

Ref: 3D-QGC39047