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CAS 141549-75-9

:

Indisetron

Description:
Indisetron, identified by its CAS number 141549-75-9, is a chemical compound that belongs to the class of serotonin 5-HT3 receptor antagonists. It is primarily utilized in the medical field for its antiemetic properties, particularly in the prevention and treatment of nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative recovery. The compound works by blocking the action of serotonin at the 5-HT3 receptors in the central nervous system and gastrointestinal tract, thereby mitigating the signals that trigger nausea. Indisetron is characterized by its relatively high potency and selectivity for the 5-HT3 receptor, making it effective in clinical applications. Its pharmacokinetic profile typically includes rapid absorption and a moderate half-life, allowing for effective dosing regimens. As with many pharmaceuticals, potential side effects may include headache, dizziness, and gastrointestinal disturbances, although these are generally mild. Overall, Indisetron represents a significant advancement in the management of nausea and vomiting in various medical contexts.
Formula:C17H23N5O
InChI:InChI=1/C17H23N5O/c1-21-9-12-7-11(8-13(10-21)22(12)2)18-17(23)16-14-5-3-4-6-15(14)19-20-16/h3-6,11-13H,7-10H2,1-2H3,(H,18,23)(H,19,20)/t11-,12-,13+
InChI key:InChIKey=MHNNVDILNTUWNS-XYYAHUGANA-N
SMILES:C(N[C@H]1C[C@@]2(N(C)[C@](C1)(CN(C)C2)[H])[H])(=O)C=3C=4C(NN3)=CC=CC4
Synonyms:
  • 1H-Indazole-3-carboxamide, N-(3,9-dimethyl-3,9-diazabicyclo[3.3.1]non-7-yl)-, endo-
  • 1H-Indazole-3-carboxamide, N-[(7-endo)-3,9-dimethyl-3,9-diazabicyclo[3.3.1]non-7-yl]-
  • 3,9-Diazabicyclo[3.3.1]nonane, 1H-indazole-3-carboxamide deriv.
  • Indisetron [INN]
  • N-(3,9-Dimethyl-endo-3,9-diazabicyclo(3.3.1)non-7-yl)-1H-indazole-3-carboxamide
  • N-(3,9-dimethyl-3,9-diazabicyclo[3.3.1]non-7-yl)-1H-indazole-3-carboxamide
  • N-[(7-endo)-3,9-Dimethyl-3,9-diazabicyclo[3.3.1]non-7-yl]-1H-indazole-3-carboxamide
  • Unii-89Rbz66Nvc
  • Indisetron
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Found 2 products.
  • Indisetron
    TLC
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    Indisetron

    CAS:
    Formula:C17H23N5O
    Color and Shape:White To Off-White Solid
    Molecular weight:313.41

    Ref: 4Z-I-089001

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  • Indisetron
    TRC
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    Indisetron

    Controlled Product
    CAS:

    Applications A 5-HT3 receptor antagonist as an antiemetic agent. It is used for treatment of digestive tract disorders.
    References Merrifield, K., et al.: Clin. Pharm., 8, 187 (1989), Joss, R., et al.: Eur. J. Cancer., 26, 2 (1990), Mitchelson, F., et al.: Drugs, 43, 295 (1992), Hoshino, E., et al.: J. Clin. Ther. Med., 12, 2483 (1996),

    Formula:C17H23N5O
    Color and Shape:Neat
    Molecular weight:313.4

    Ref: TR-I532500

    1mg
    336.00€
    10mg
    2,294.00€