CAS 14158-66-8

Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, hydrochloride, (Z)-

Description:

Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, hydrochloride, commonly referred to by its CAS number 14158-66-8, is a chemical compound characterized by its complex structure, which includes a triethylamine moiety and a phenoxy group substituted with a chlorinated diphenylvinyl group. This compound typically appears as a white to off-white solid and is soluble in polar solvents, reflecting its ionic nature due to the hydrochloride form. It exhibits basic properties due to the presence of the triethylamine component, which can participate in protonation reactions. The chlorinated diphenylvinyl group may impart specific electronic and steric properties, influencing its reactivity and potential applications in organic synthesis or medicinal chemistry. Additionally, the compound may exhibit biological activity, making it of interest in pharmacological research. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper precautions are taken due to potential toxicity or reactivity.

Formula: C₂₆H₂₈ClNO·ClH

InChI: InChI=1S/C26H28ClNO.ClH/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;/h5-18H,3-4,19-20H2,1-2H3;1H/b26-25-;

InChI key: InChIKey=KKBZGZWPJGOGJF-OQKDUQJOSA-N

SMILES: C(=C(\Cl)/C1=CC=CC=C1)(\C2=CC=C(OCCN(CC)CC)C=C2)/C3=CC=CC=C3.Cl

Synonyms:

• Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, hydrochloride, (Z)-

cis-Clomiphene Hydrochloride

Controlled Product

CAS: 14158-66-8

Applications Cis isomer of Clomiphene (C587025). Found to be antiestrogenic and a less potent inhibitor of LH secretion than the trans isomer.
References Robert, B.S.: J. Anim. Sci., 33, 607 (1971); Weissenberg, R.: Andrologia, 24, 162 (1992); Palopoli, F.P., J. Med. Chem., 10, 84 (1967); Ernst., et al.: J. Pharm. Sci., 65, 148 (1976); Baustian, C.L., et al.: Pharm. Biomed. Anal., 4, 237 (1986); Schally, A.V., et al.: Vitam. Horm., 30, 146 (1973)

Formula: C₂₆H₂₉Cl₂NO

Color and Shape: White To Off-White

Molecular weight: 442.42

Ref: TR-C587030

cis-Clomiphene-d5 Hydrochloride

Controlled Product

CAS: 1346747-53-2, 14158-66-8

Formula: C₂₆D₅H₂₃ClNO·HCl

Color and Shape: Neat

Molecular weight: 447.451

Ref: TR-C587032