CAS 141595-53-1

N,N-hexamethylenecarbamoyl-leu-N-*formyl-D-trp-D-

Description:

N,N-hexamethylenecarbamoyl-leu-N-formyl-D-tryptophan (CAS 141595-53-1) is a synthetic compound that belongs to the class of peptide derivatives. It features a hexamethylene chain that connects a carbamoyl group to a leucine residue, along with a formylated D-tryptophan moiety. This structure suggests that it may exhibit properties typical of peptides, such as potential biological activity and interactions with specific receptors or enzymes. The presence of the formyl group can influence its reactivity and solubility, while the D-amino acid configuration may affect its stability and resistance to enzymatic degradation. The compound is likely to be of interest in biochemical research, particularly in studies related to peptide synthesis, drug design, or as a potential therapeutic agent. Its specific characteristics, such as solubility, melting point, and biological activity, would require empirical investigation to fully understand its behavior in various environments.

Formula: C₃₆H₄₄N₆O₆

InChI: InChI=1/C36H44N6O6/c1-23(2)17-29(40-36(48)41-15-9-3-4-10-16-41)33(44)38-30(19-25-21-42(22-43)32-14-8-6-12-27(25)32)34(45)39-31(35(46)47)18-24-20-37-28-13-7-5-11-26(24)28/h5-8,11-14,20-23,29-31,37H,3-4,9-10,15-19H2,1-2H3,(H,38,44)(H,39,45)(H,40,48)(H,46,47)/t29-,30+,31+/m0/s1

Synonyms:

• N-(azepan-1-ylcarbonyl)-L-leucyl-1-formyl-D-tryptophyl-D-tryptophan
• Bq-610

BQ-610

CAS: 141595-53-1

BQ-610 is a very potent ET-A receptor antagonist which is about 30000 times more selective for ET-A receptors than for ET-B receptors. Furthermore, it has been found that BQ-610 strongly antagonizes ET-1 induced concentration in porcine coronary artery with a pA₂ value of 8.2.

Formula: C₃₆H₄₄N₆O₆

Purity: > 95%

Molecular weight: 656.78

Ref: 01-4034542

D-Tryptophan, N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-1-formyl-D-tryptophyl-

CAS: 141595-53-1

Formula: C₃₆H₄₄N₆O₆

Molecular weight: 656.7712

Ref: IN-DA001GNK

BQ-610

CAS: 141595-53-1

BQ-610 is a drug that has been shown to improve brain functions and energy metabolism. It also inhibits the transmission of pain signals in the mesenteric region of rats by blocking voltage-dependent calcium channels. BQ-610 is found to suppress the production of endothelin-a receptor, which is an important regulator for many diseases such as infectious diseases, hypertension, and other cardiovascular disorders. The drug has also been shown to reduce oxidative stress by inhibiting cell nuclei and reducing inflammation by inhibiting basic protein synthesis. BQ-610 has been shown to be effective against congestive heart failure in rats by increasing blood flow and improving biochemical properties.

Formula: C₃₆H₄₄N₆O₆

Purity: Min. 95%

Molecular weight: 656.79 g/mol

Ref: 3D-PED-3610-PI

BQ-610

CAS: 141595-53-1

BQ-610 is an Endothelin A receptor antagonist.

Formula: C₃₆H₄₄N₆O₆

Color and Shape: Solid

Molecular weight: 656.77

Ref: TM-T70727

BQ-610 Azepane-1-carbonyl-Leu-D-Trp(For)-D-Trp-OH

CAS: 141595-53-1

BQ-610 is a novel peptide that has been shown to reduce the severity of mucosal inflammation in animal models of inflammatory bowel disease. It functions by binding to myofibroblasts, which are cells that produce an extracellular matrix and collagen. BQ-610 also blocks signalling pathways that are responsible for the production of TNF-α, MMP-2, and other molecules involved in the pathogenesis of inflammatory bowel disease. BQ-610 is effective at reducing inflammation in animal models of colitis, but not in human colonic epithelial cells or human colonic tissue.

Formula: C₃₆H₄₄N₆O₆

Purity: Min. 95%

Molecular weight: 656.77 g/mol

Ref: 3D-FB109401