CAS 141625-93-6: Dronedarone hydrochloride

Description: Dronedarone hydrochloride is a pharmaceutical compound primarily used in the management of atrial fibrillation and atrial flutter, conditions characterized by irregular heartbeats. It is classified as an antiarrhythmic agent and is structurally related to amiodarone, although it has a more favorable side effect profile. The substance is a white to off-white crystalline powder that is soluble in water and exhibits a moderate lipophilicity. Dronedarone functions by blocking various ion channels, including sodium, potassium, and calcium channels, which helps to stabilize the cardiac rhythm. Its pharmacokinetics involve extensive hepatic metabolism, primarily via cytochrome P450 enzymes, and it has a relatively short half-life compared to amiodarone. The hydrochloride salt form enhances its solubility and bioavailability. Common side effects may include gastrointestinal disturbances, liver enzyme elevations, and potential cardiovascular effects, necessitating careful monitoring during treatment. Overall, Dronedarone hydrochloride represents an important therapeutic option for patients with specific cardiac arrhythmias.

Formula: C₃₁H₄₅ClN₂O₅S

InChI: InChI=1/C31H44N2O5S.ClH/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3;/h13-18,23,32H,5-12,19-22H2,1-4H3;1H

Synonyms:

• Dronedarone HCl
• N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide hydrochloride (1:1)
• Dronedarone Intermediate 1

Dronedarone hydrochloride CRS

CAS: 141625-93-6

• Color and Shape: Powder

Dronedarone Hydrochloride

CAS: 141625-93-6

Sulfonamides used as drugs

• Formula: C₃₁H₄₄N₂O₅S·HCl
• Color and Shape: Powder
• Molecular weight: 592.27377

Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1)

CAS: 141625-93-6

• Formula: C₃₁H₄₅ClN₂O₅S
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 593.2174

Dronedarone hydrochloride

CAS: 141625-93-6

Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for …

• Formula: C₃₁H₄₄N₂O₅S·HCl
• Purity: 99.91%
• Color and Shape: Solid
• Molecular weight: 593.22

Dronedarone HCl

CAS: 141625-93-6

• Formula: C₃₁H₄₄N₂O₅S·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 556.76 36.46

Dronedarone hydrochloride

CAS: 141625-93-6

• Formula: C₃₁H₄₄N₂O₅S·HCl
• Purity: (Titration) ≥ 98.0% (dried basis)
• Color and Shape: White to off-white powder
• Molecular weight: 593.22

Dronedarone Hydrochloride

CAS: 141625-93-6

• Purity: 98%+
• Molecular weight: 593.22g/mol

Dronedarone Hydrochloride

CAS: 141625-93-6141626-36-0

• Formula: C₃₁H₄₄N₂O₅S·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 593.22

Dronedarone Hydrochloride

CAS: 141625-93-6

Stability Hygroscopic Applications A drug used for the treatment of atrial fibrillation and atrial flutter …

• Formula: C₃₁H₄₄N₂O₅S·ClH
• Color and Shape: Neat
• Molecular weight: 593.22

Dronedarone hydrochloride

CAS: 141625-93-6

Multichannel blocker; reduces sodium and calcium currents

• Formula: C₃₁H₄₄N₂O₅S•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 593.22 g/mol

Dronedarone HCl - Bio-X ™

CAS: 141625-93-6

Dronedarone is a novel class III anti-arrhythmic drug. It has been shown to be effective …

• Formula: C₃₁H₄₄N₂O₅S•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 593.22 g/mol