CAS 14166-21-3

trans-1,2-cyclohexanedicarboxylic anhydride

Description:

Trans-1,2-cyclohexanedicarboxylic anhydride, with the CAS number 14166-21-3, is a cyclic anhydride derived from cyclohexanedicarboxylic acid. This compound features a six-membered carbon ring with two carboxylic acid groups that have undergone dehydration to form an anhydride. Its structure imparts unique characteristics, including a relatively high melting point and stability under standard conditions. The trans configuration of the substituents around the ring contributes to its rigidity and influences its reactivity. This anhydride is typically used in organic synthesis and as an intermediate in the production of various chemical compounds, including polymers and resins. It can participate in reactions typical of anhydrides, such as nucleophilic acyl substitution, making it valuable in the synthesis of esters and amides. Additionally, it may exhibit moderate solubility in organic solvents, which is important for its applications in chemical processes. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₈H₁₀O₃

InChI: InChI=1/C16H22O7/c17-13(18)9-5-1-3-7-11(9)15(21)23-16(22)12-8-4-2-6-10(12)14(19)20/h9-12H,1-8H2,(H,17,18)(H,19,20)/t9-,10+,11-,12+

InChI key: InChIKey=MUTGBJKUEZFXGO-IOMOGOHMNA-N

SMILES: O=C1[C@@]2([C@@](C(=O)O1)(CCCC2)[H])[H]

Synonyms:

• 1,2-Cyclohexanedicarboxylic anhydride, trans-
• 1,3-Isobenzofurandione, hexahydro-, (3aR,7aR)-rel-
• 1,3-Isobenzofurandione, hexahydro-, trans-
• dl-trans-1,2-Cyclohexanedicarboxylic anhydride
• rel-(3aR,7aR)-Hexahydro-1,3-isobenzofurandione
• rel-(3aS,7aS)-Hexahydroisobenzofuran-1,3-dione
• trans-Cyclohexane-1,2-dicarboxylic acid anhydride
• trans-Cyclohexane-1,2-dicarboxylic anhydride
• trans-Hexahydrophthalic anhydride
• trans-1,2-Cyclohexanedicarboxylic anhydride
• cis-1.2-Cyclohexane dicarboxylic anhydride 1g [14166-21-3]
• trans-1,2-Cyclohexanedicarboxylic anhydride 97%
• trans-Hexahydroisobenzofuran-1,3-dione
• trans-1,2-Cyclohexanedicarboxylic anhydride,trans-Hexahydrophthalic anhydride

(±)-trans-1,2-Cyclohexanedicarboxylic Anhydride

CAS: 14166-21-3

Formula: C₈H₁₀O₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 154.17

Ref: 3B-C1657

trans-Hexahydroisobenzofuran-1,3-dione

CAS: 14166-21-3

Formula: C₈H₁₀O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 154.1632

Ref: IN-DA0035Q0

Trans-Hexahydroisobenzofuran-1,3-Dione

CAS: 14166-21-3

Trans-Hexahydroisobenzofuran-1,3-Dione

Purity: 98%

Molecular weight: 154.16g/mol

Ref: 54-OR1030222

trans-1,2-Cyclohexanedicarboxylic acid anhydride

CAS: 14166-21-3

Formula: C₈H₁₀O₃

Color and Shape: Neat

Molecular weight: 154.16

Ref: 04-C11824515

Trans-1,2-cyclohexanedicarboxylic Anhydride

Controlled Product

CAS: 14166-21-3

Stability Moisture Sensitive
Applications Trans-1,2-cyclohexanedicarboxylic anhydride can be used as a reagent to prepare hepatitis C virus (HCV) and granzyme B (indoline derivatives) inhibitors. It has also been employed in studies relating to the development of protein kinase C inhibitors.
References Yang, Z., et al.: PCT Int. Appl. WO 2015124063 A1 20150827 (2015); Cameron, D. R. PCT Int. Appl. WO 2014153666 A1 20141002 (2014); Cameron, D. R. PCT Int. Appl. WO 2014153666 A1 20141002 (2014); Lampe, J. W., et al.: J. Med. Chem 45, 2624

Formula: C₈H₁₀O₃

Color and Shape: Neat

Molecular weight: 154.16

Ref: TR-C987290