CAS 1416992-39-6

GC376

Description:

GC376 is a synthetic compound that has garnered attention primarily for its antiviral properties, particularly against coronaviruses. It is classified as a peptidomimetic compound, which means it mimics the structure of peptides but is not composed of amino acids. GC376 functions as a protease inhibitor, specifically targeting the main protease of coronaviruses, thereby disrupting their replication cycle. This mechanism of action makes it a candidate for therapeutic use in treating viral infections, including those caused by coronaviruses like SARS-CoV and MERS-CoV. The compound has shown promise in preclinical studies, demonstrating efficacy in inhibiting viral replication. Additionally, GC376 has been investigated for its potential use in veterinary medicine, particularly in treating feline infectious peritonitis (FIP), a serious viral disease in cats. Its chemical structure and properties contribute to its stability and bioavailability, making it a subject of ongoing research in the field of antiviral drug development.

(βS)-α-Hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid sodium salt

CAS: 1416992-39-6

Formula: C₂₁H₃₀N₃NaO₈S

Purity: 98%

Color and Shape: Solid

Molecular weight: 507.5330

Ref: IN-DA01K3ET

GC376 sodium

CAS: 1416992-39-6

GC376 sodium

Purity: ≥95%

Molecular weight: 507.53g/mol

Ref: 54-BUP12515

GC376

CAS: 1416992-39-6

GC376

Formula: C₂₁H₃₀N₃O₈S·Na

Purity: 98%

Color and Shape: white solid

Molecular weight: 507.53296g/mol

Ref: 54-BISN0327

GC376 sodium

CAS: 1416992-39-6

GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.

Formula: C₂₁H₃₀N₃NaO₈S

Purity: 95% - 98%

Color and Shape: Solid

Molecular weight: 507.53

Ref: TM-T5188

GC376 sodium

CAS: 1416992-39-6

GC 376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC 376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.

Formula: C₂₁H₃₀N₃NaO₈S

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 507.53 g/mol

Ref: 3D-BG167367