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CAS 141743-16-0

:

FMOC-N-(TERT-BUTYLOXYCARBONYLMETHYL)-GLYCINE

Description:
FMOC-N-(tert-butyloxycarbonylmethyl)-glycine is a chemical compound commonly used in peptide synthesis and organic chemistry. It features a fluoromethoxycarbonyl (FMOC) protecting group, which is widely utilized for the protection of amines during peptide synthesis, allowing for selective reactions without interference from the amine functionality. The tert-butyloxycarbonyl (Boc) group provides additional protection for the amino group, enhancing the stability of the compound under various reaction conditions. This compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but it is less soluble in water. Its structure includes a glycine moiety, which contributes to its role in peptide synthesis. The presence of both FMOC and Boc groups allows for sequential deprotection strategies, making it a valuable intermediate in the synthesis of more complex peptides and pharmaceuticals. As with many chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its use.
Formula:C23H25NO6
Synonyms:
  • Fmoc-Nasp(Otbu)-Oh
  • Fmoc-N-(tert-butoxycarbonylmethyl)-glycine
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