CAS 141758-74-9
:exendin-4
Description:
Exendin-4 is a synthetic peptide that mimics the action of the glucagon-like peptide-1 (GLP-1), a hormone involved in glucose metabolism and insulin secretion. It is primarily used in the treatment of type 2 diabetes due to its ability to enhance insulin secretion in response to elevated blood glucose levels, inhibit glucagon release, and promote satiety, thereby aiding in weight management. Exendin-4 has a molecular formula that reflects its peptide structure, consisting of a sequence of amino acids that contribute to its biological activity. The substance is characterized by its stability and prolonged action compared to endogenous GLP-1, making it a valuable therapeutic agent. It is typically administered via subcutaneous injection and has been studied for its potential cardiovascular benefits. As a peptide, exendin-4 is sensitive to degradation by proteolytic enzymes, which is a consideration in its formulation and delivery. Overall, exendin-4 represents a significant advancement in diabetes management, offering a multifaceted approach to controlling blood sugar levels.
Formula:C184H282N50O60S
InChI:InChI=1S/C184H282N50O60S/c1-16-94(10)147(178(289)213-114(52-58-144(257)258)163(274)218-121(73-101-77-195-105-39-24-23-38-103(101)105)168(279)215-116(68-90(2)3)165(276)205-107(41-26-28-61-186)158(269)219-122(75-134(189)243)154(265)198-79-135(244)196-83-139(248)231-63-30-43-129(231)175(286)225-127(87-238)174(285)223-125(85-236)155(266)200-80-136(245)202-96(12)181(292)233-65-32-45-131(233)183(294)234-66-33-46-132(234)182(293)232-64-31-44-130(232)176(287)222-124(84-235)150(190)261)229-170(281)119(71-99-34-19-17-20-35-99)217-166(277)117(69-91(4)5)214-159(270)108(42-29-62-194-184(191)192)212-177(288)146(93(8)9)228-151(262)95(11)203-156(267)111(49-55-141(251)252)208-161(272)112(50-56-142(253)254)209-162(273)113(51-57-143(255)256)210-164(275)115(59-67-295-15)211-160(271)110(47-53-133(188)242)207-157(268)106(40-25-27-60-185)206-172(283)126(86-237)224-167(278)118(70-92(6)7)216-169(280)123(76-145(259)260)220-173(284)128(88-239)226-180(291)149(98(14)241)230-171(282)120(72-100-36-21-18-22-37-100)221-179(290)148(97(13)240)227-138(247)82-199-153(264)109(48-54-140(249)250)204-137(246)81-197-152(263)104(187)74-102-78-193-89-201-102/h17-24,34-39,77-78,89-98,104,106-132,146-149,195,235-241H,16,25-33,40-76,79-88,185-187H2,1-15H3,(H2,188,242)(H2,189,243)(H2,190,261)(H,193,201)(H,196,244)(H,197,263)(H,198,265)(H,199,264)(H,200,266)(H,202,245)(H,203,267)(H,204,246)(H,205,276)(H,206,283)(H,207,268)(H,208,272)(H,209,273)(H,210,275)(H,211,271)(H,212,288)(H,213,289)(H,214,270)(H,215,279)(H,216,280)(H,217,277)(H,218,274)(H,219,269)(H,220,284)(H,221,290)(H,222,287)(H,223,285)(H,224,278)(H,225,286)(H,226,291)(H,227,247)(H,228,262)(H,229,281)(H,230,282)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H4,191,192,194)/t94-,95-,96-,97+,98+,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,146-,147-,148-,149-/m0/s1
Synonyms:- H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
- Exenatide
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Found 15 products.
Exenatide
CAS:Exendin-4 (exenatide), originally isolated from Heloderma suspectum venom, differs from exendin-3 by only 2 N-terminal amino acid substitutions. This polypeptide causes an increase in acinar cAMP without stimulating amylase release. Exendin-4 and glucagon-like peptide 1 (7-36) amide bind with similar affinity to the glucagon-like peptide 1 receptor. Moreover, exendin-4 is also considered for clinical use in the treatment of type 2 diabetes.Formula:C184H282N50O60SPurity:97.18%Color and Shape:WhiteMolecular weight:4186.63Exenatide
CAS:<p>Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi</p>Formula:C184H282N50O60SColor and Shape:White PowderMolecular weight:4184.02731Exenatide
CAS:<p>Exenatide</p>Purity:(hplc): >96% (Typical Value in Batch COA)Color and Shape: white powderMolecular weight:4,246.62g/molExenatide acetate
CAS:Formula:C186H286N50OPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:4246.62Exendin-4
CAS:Formula:C184H282N50O60SPurity:(HPLC) ≥ 95.0%Color and Shape:White solidMolecular weight:4186.56Exendin-4
CAS:<p>Exenatide: GLP-1 receptor agonist, 39-amino acid, longer half-life (2.4 hrs), IC50 of 3.22 nM.</p>Formula:C184H282N50O60SPurity:97.71% - 99.78%Color and Shape:SolidMolecular weight:4186.57Exenatide
CAS:<p>Agonist of glucagon-like peptide GLP-1 receptor</p>Formula:C184H282N50O60SPurity:Min. 94 Area-%Color and Shape:White PowderMolecular weight:4,186.57 g/molExendin-4
CAS:<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>Formula:C184H282N50O60SMolecular weight:4,186.63 g/molExendin-4
CAS:<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>Formula:C184H282N50O60SMolecular weight:4,186.7 g/molExendin-4 TFA salt
CAS:<p>Synthetic peptide whose sequence was originally isolated from venom derived from the modified salivary glands of the Gila monster (Heloderma suspectum). This product has the potential to be applied as a GLP-1 (Glucagon-Like Peptide-1) Receptor Agonist and is available in the trifluoroacetate salt form.</p>Formula:C184H282N50O60SPurity:Min. 95%Molecular weight:4,186.66 g/molExendin 4
CAS:<p>Custom research peptide; min purity 95%.</p>Formula:C184H282N50O60S1Purity:Min. 95%Molecular weight:4,186.03 g/molExendin 4 (Heloderma suspectum)
CAS:Formula:C184H282N50O60SPurity:98%Color and Shape:SolidMolecular weight:4186.571879999979
