6-Chloro-2'-deoxyguanosine is a modified nucleoside that serves as an important building block in the study of nucleic acids and their interactions. It is characterized by the presence of a chlorine atom at the 6-position of the guanine base, which alters its chemical properties and biological activity compared to unmodified deoxyguanosine. This modification can influence the nucleoside's ability to participate in base pairing and its overall stability within DNA structures. The compound is often utilized in research related to DNA synthesis, mutagenesis, and the development of antiviral and anticancer therapies. Its unique structure allows it to be incorporated into DNA, where it may affect replication and transcription processes. Additionally, 6-Chloro-2'-deoxyguanosine can serve as a substrate for various enzymes involved in nucleic acid metabolism, making it a valuable tool in biochemical studies. As with many nucleoside analogs, its pharmacological properties and potential therapeutic applications are of significant interest in medicinal chemistry.

6-Chloro-2'-deoxyguanosine

141771-78-0: 6-Chloro-2'-deoxyguanosine is a modified nucleoside that serves as an important building block in the study of nucleic acids and their interactions. It is characterized by the presence of a chlorine atom at the 6-position of the guanine base, which alters its chemical properties and biological activity compared to unmodified deoxyguanosine. This modification can influence the nucleoside's ability to participate in base pairing and its overall stability within DNA structures. The compound is often utilized in research related to DNA synthesis, mutagenesis, and the development of antiviral and anticancer therapies. Its unique structure allows it to be incorporated into DNA, where it may affect replication and transcription processes. Additionally, 6-Chloro-2'-deoxyguanosine can serve as a substrate for various enzymes involved in nucleic acid metabolism, making it a valuable tool in biochemical studies. As with many nucleoside analogs, its pharmacological properties and potential therapeutic applications are of significant interest in medicinal chemistry.

6-Chloro-2''-deoxyguanosine

<p>6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine is a novel antiviral and anticancer agent. It is an analog of adenosine that inhibits viral replication by inhibiting DNA synthesis. 6CePP2A is an activator of nucleoside deoxyribonucleotidyltransferase, which converts dATP to dTTP.</p>

CAS 141771-78-0

6-Chloro-2'-deoxyguanosine

6-Chloro-2''-deoxyguanosine

Ref: 7W-GN8943

6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine

Ref: 3D-NC02987