CAS 141776-91-2

3,5-Difluorobenzyl bromide

Description:

3,5-Difluorobenzyl bromide is an organic compound characterized by the presence of a benzyl group substituted with two fluorine atoms at the 3 and 5 positions and a bromine atom at the benzyl carbon. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity due to the presence of the bromine atom, which can participate in nucleophilic substitution reactions. The fluorine substituents contribute to the compound's unique electronic properties, influencing its polarity and reactivity. 3,5-Difluorobenzyl bromide is often utilized in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, due to its ability to serve as a versatile building block. It is important to handle this compound with care, as it may pose health risks, including irritation to the skin and eyes, and should be used in a well-ventilated area with appropriate personal protective equipment. As with many halogenated compounds, environmental considerations regarding its disposal and potential toxicity should also be taken into account.

Formula: C₁₅H₃F₂₉O₅

InChI: InChI=1/C15H3F29O5/c16-2(1-45,7(22,23)24)46-13(39,40)4(19,9(28,29)30)48-15(43,44)6(21,11(34,35)36)49-14(41,42)5(20,10(31,32)33)47-12(37,38)3(17,18)8(25,26)27/h45H,1H2

SMILES: C(C(C(F)(F)F)(F)OC(C(C(F)(F)F)(F)OC(C(C(F)(F)F)(F)OC(C(C(F)(F)F)(F)OC(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O

Synonyms:

• 1-(Brommethyl)-3,5-difluorbenzol
• 1-(Bromomethyl)-3,5-difluorobenzene
• 141776-91-2
• Benzene, 1-(bromomethyl)-3,5-difluoro-
• Fr Cf E1E
• 2,4,4,5,7,7,8,10,10,11,13,13,14,14,15,15,15-Heptadecafluoro-2,5,8,11-Tetrakis(Trifluoromethyl)-3,6,9,12-Tetraoxapentadecan-1-Ol
• 5-Fluoro-2-formylbenzeneboronic acid
• 5-Fluoro-2-formylphenylboronic acid

3,5-Difluorobenzyl Bromide

CAS: 141776-91-2

Formula: C₇H₅BrF₂

Purity: >98.0%(GC)

Color and Shape: Colorless to Orange to Green clear liquid

Molecular weight: 207.02

Ref: 3B-D2631

Benzene, 1-(bromomethyl)-3,5-difluoro-

CAS: 141776-91-2

Formula: C₇H₅BrF₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 207.0154

Ref: IN-DA001H16

3,5-Difluorobenzyl bromide

CAS: 141776-91-2

Formula: C₇H₅BrF₂

Molecular weight: 207.02

Ref: 7W-GK9491

3,5-Difluorobenzyl bromide

CAS: 141776-91-2

3,5-Difluorobenzyl bromide

Formula: C₇H₅BrF₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 207.0154g/mol

Ref: 54-PC2746

3,5-Difluorobenzyl bromide

CAS: 141776-91-2

Formula: C₇H₅BrF₂

Purity: 95%

Color and Shape: Liquid, Clear

Molecular weight: 207.018

Ref: 10-F004798

3,5-Difluorobenzyl bromide

CAS: 141776-91-2

3,5-Difluorobenzyl bromide (3,5-DFB) is a molecule that is used to inhibit the activity of protein kinases. It binds to the ATP binding site of these enzymes and prevents ATP from binding. This leads to a reduced ability of the protein kinase to phosphorylate other proteins. 3,5-Difluorobenzyl bromide has been shown to inhibit influenza virus replication in vitro and in vivo. X-ray crystal structures have shown that 3,5-DFB binds to an active site on the viral RNA polymerase complex, where it interacts with viral nucleotides and blocks their incorporation into viral RNA chains. 3,5-DFB also inhibits virus strain A/WSN/33 (H1N1) in cell culture at concentrations of 5 μM or less.

Formula: C₇H₅BrF₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 207.02 g/mol

Ref: 3D-FD49123