CAS 1418308-27-6

6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide

Description:

The chemical substance known as 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide, with the CAS number 1418308-27-6, is a complex organic compound characterized by its unique structural features. It contains an indole core, which is a bicyclic structure known for its presence in many biologically active compounds. The presence of a cyano group (–CN) and a carboxamide functional group (–CONH2) suggests potential reactivity and solubility in polar solvents. The compound also features a pyridine derivative, contributing to its potential pharmacological properties. The presence of multiple methyl groups indicates a degree of hydrophobicity, which may influence its interaction with biological membranes. Overall, this compound may exhibit interesting biological activities, making it a candidate for further research in medicinal chemistry and drug development. However, specific properties such as melting point, solubility, and biological activity would require empirical investigation to fully characterize its behavior and applications.

Formula: C₂₃H₂₆N₄O₂

InChI: InChI=1S/C23H26N4O2/c1-5-17(6-2)27-8-7-18-19(10-16(12-24)11-21(18)27)22(28)25-13-20-14(3)9-15(4)26-23(20)29/h7-11,17H,5-6,13H2,1-4H3,(H,25,28)(H,26,29)

InChI key: InChIKey=PFHDWRIVDDIFRP-UHFFFAOYSA-N

SMILES: C(CC)(CC)N1C=2C(=C(C(NCC3=C(C)C=C(C)NC3=O)=O)C=C(C#N)C2)C=C1

Synonyms:

• 1H-Indole-4-carboxamide, 6-cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-
• EL 1
• 1EI1
• 6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide
• EI 1
• 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide
• Ezh2 inhibitorEI

EI1

CAS: 1418308-27-6

Formula: C₂₃H₂₆N₄O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 390.4781

Ref: IN-DA009CB9

6-Cyano-N-((4,6-Dimethyl-2-Oxo-1,2-Dihydropyridin-3-Yl)Methyl)-1-(Pentan-3-Yl)-1H-Indole-4-Carboxamide

CAS: 1418308-27-6

6-Cyano-N-((4,6-Dimethyl-2-Oxo-1,2-Dihydropyridin-3-Yl)Methyl)-1-(Pentan-3-Yl)-1H-Indole-4-Carboxamide

Purity: 98%

Molecular weight: 390.48g/mol

Ref: 54-OR1023180

EI1

CAS: 1418308-27-6

EI1

Purity: ≥98%

Molecular weight: 390.48g/mol

Ref: 54-BUP10687

EI1

CAS: 1418308-27-6

EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.

Formula: C₂₃H₂₆N₄O₂

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 390.48

Ref: TM-T6484