CAS 14192-26-8

2-Oxo-2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester

Description:

2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester, with the CAS number 14192-26-8, is a chemical compound that belongs to the class of indole derivatives. This substance features a bicyclic structure characteristic of indoles, which are known for their diverse biological activities. The presence of a carboxylic acid methyl ester group indicates that it can undergo hydrolysis to yield the corresponding carboxylic acid, making it potentially useful in various synthetic applications. The compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its oxo and dihydro functionalities suggest it may participate in various chemical reactions, including nucleophilic attacks and condensation reactions. Additionally, compounds of this nature are often investigated for their pharmacological properties, including anti-inflammatory and antimicrobial activities. As with many organic compounds, handling should be done with care, considering potential toxicity and reactivity. Overall, 2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester is a versatile compound with potential applications in medicinal chemistry and organic synthesis.

Formula: C₁₀H₉NO₃

InChI: InChI=1S/C10H9NO3/c1-14-10(13)7-3-2-6-5-9(12)11-8(6)4-7/h2-4H,5H2,1H3,(H,11,12)

InChI key: InChIKey=YFTGUNWFFVDLNM-UHFFFAOYSA-N

SMILES: C(OC)(=O)C=1C=C2C(CC(=O)N2)=CC1

Synonyms:

• 1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester
• 2-Oxo-2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester
• 6-(Methoxycarbonyl)-2-indolone
• 6-Carbomethoxy-2-Oxindole
• 6-Indolinecarboxylic acid, 2-oxo-, methyl ester
• 6-Methoxycarbonyl-2-oxindole
• 6-carboxylic acid methyl Indole-2-one
• Methyl 2-Oxoindoline-6-carboxylate
• Methyl 2-oxindole-6-carboxylate
• Methyl 2-oxoindole-6-carboxylate
• Oxindole-6-carboxylic acid methyl ester
• methyl 2-oxo-2,3-dihydro-1H-indole-6-carboxylate
• Methyl  oxindole-6-carboxylate

1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester

CAS: 14192-26-8

Formula: C₁₀H₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.1834

Ref: IN-DA001HDX

Nintedanib Impurity 98

CAS: 14192-26-8

Formula: C₁₀H₉NO₃

Molecular weight: 191.19

Ref: 4Z-N-066111

Methyl 2-Oxoindoline-6-carboxylate

CAS: 14192-26-8

Formula: C₁₀H₉NO₃

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 191.19

Ref: 3B-M2799

Methyl oxindole-6-carboxylate

CAS: 14192-26-8

Methyl oxindole-6-carboxylate

Formula: C₁₀H₉NO₃

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 191.18g/mol

Ref: 54-OR5623

Methyl Oxindole-6-carboxylate

Controlled Product

CAS: 14192-26-8

Applications Methyl Oxindole-6-carboxylate is an intermediate used to prepare BIBF 1120, an indolinone as triple angiokinase inhibitors.
References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009)

Formula: C₁₀H₉NO₃

Color and Shape: Off-White

Molecular weight: 191.18

Ref: TR-M315030

Methyl 2-oxoindole-6-carboxylate

CAS: 14192-26-8

Intermediate in the synthesis of nintedanib

Formula: C₁₀H₉NO₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 191.18 g/mol

Ref: 3D-FM45502

Methyl oxindole-6-carboxylate

CAS: 14192-26-8

Formula: C₁₀H₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.186

Ref: 10-F093037

Nintedanib Impurity 52

CAS: 14192-26-8

Formula: C₁₀H₉NO₃

Molecular weight: 191.19

Ref: ST-EA-CP-N24047