CAS 141942-85-0

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate

Description:

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, with the CAS number 141942-85-0, is a chiral compound that belongs to the class of cyano derivatives. It features a cyano group (-C≡N) and a hydroxyl group (-OH) attached to a butyric acid backbone, which contributes to its biological activity. The presence of the ethyl ester group enhances its solubility in organic solvents, making it useful in various chemical reactions and applications. This compound is often utilized in the synthesis of pharmaceuticals and agrochemicals due to its ability to serve as an intermediate in the production of more complex molecules. Its chirality, indicated by the (R)- configuration, is significant in determining its interaction with biological systems, as enantiomers can exhibit different pharmacological effects. Additionally, the compound's stability and reactivity can be influenced by factors such as pH and temperature, which are important considerations in its handling and application in synthetic processes.

Formula: C₇H₁₁NO₃

InChI: InChI=1/C7H11NO3/c1-2-11-7(10)5-6(9)3-4-8/h6,9H,2-3,5H2,1H3/t6-/m1/s1

InChI key: InChIKey=LOQFROBMBSKWQY-ZCFIWIBFSA-N

SMILES: [C@H](CC(OCC)=O)(CC#N)O

Synonyms:

• (3R)-4-cyano-3-hydroxybutyric acid ethyl ester
• (R)-(-)-4-cyano-3-hydroxybutyric acid ethyl ester
• (R)-(-)-ETHYL 4-cyano-3-hydroxybutyrate
• (R)-4-cyano-3-hydrobutyricacid ethyl ester
• (R)-Ethyl 4-cyano-3-hydroxybutanoate
• (S)-4-cyano-3-HYDROXYBUTANOATE ETHYL
• Atorvastatin Calcium Intermediate ATS-5
• Ats-5
• Butanoic acid, 4-cyano-3-hydroxy-, ethyl ester, (3R)-
• Butanoic acid, 4-cyano-3-hydroxy-, ethyl ester, (R)-
• ETHYL (3R)-4-cyano-3-HYDROXY-BUTANOATE
• ETHYL (R)-4-cyano-3-HYDROXYBUTANOATE
• ETHYL (S)-4-cyano-3-HYDROXYBUTANOATE
• Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
• Ethyl (R)-4-cyano-3-hydroxybutyrate
• Ethyl(R)-(-)-4-cyano-3-hydroxybutyrate
• (R)-4-cyano-3-hydroxybutyric
• (R)-4-Cyano-3-hydroxy butanoate
• ETHYL (S)-(+)-4-CYANO-3-HYDROXYBUTYRATE
• (S)-ETHYL-4-CYANO-3-HYDROXYBUTYRATE
• BUTANOIC ACID 4-CYANO-3-HYDROXY-ETHYL ESTER, (S)

Ethyl (R)-(-)-4-Cyano-3-hydroxybutyrate

CAS: 141942-85-0

Formula: C₇H₁₁NO₃

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 157.17

Ref: 3B-C1474

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, 98%

CAS: 141942-85-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₁₁NO₃

Purity: 98%

Color and Shape: Clear, colourless to pale yellow, liquid

Molecular weight: 157.17

Ref: 02-L19771

Butanoic acid, 4-cyano-3-hydroxy-, ethyl ester, (3R)-

CAS: 141942-85-0

Formula: C₇H₁₁NO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 157.1671

Ref: IN-DA001HFS

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate

CAS: 141942-85-0

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate

Purity: 98%

Molecular weight: 157.17g/mol

Ref: 54-OR1013125

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate

CAS: 141942-85-0

Formula: C₇H₁₁NO₃

Molecular weight: 157.17

Ref: 7W-GK4877

Atorvastatin Impurity 55

CAS: 141942-85-0

Formula: C₇H₁₁NO₃

Molecular weight: 157.17

Ref: 4Z-A-1296

(3R)-4-Cyano-3-hydroxybutanoic Acid Ethyl Ester

Controlled Product

CAS: 141942-85-0

Applications (3R)-4-Cyano-3-hydroxybutanoic Acid Ethyl Ester is used in a biocatalytic process for the synthesis of an atorvastatin intermediate and degredation products/impurities.
References Ma, S. et al.: Green Chem., 12, 81 (2010); Stach, J. et al.: Coll. Czech. Chem. Comm., 73, 229 (2008);

Formula: C₇H₁₁NO₃

Color and Shape: Neat

Molecular weight: 157.17

Ref: TR-E905900

Atorvastatin Impurity 18

CAS: 141942-85-0

Formula: C₇H₁₁NO₃

Molecular weight: 157.17

Ref: ST-EA-CP-A32097

(R)-4-Cyano-3-hydroxy-butyric acid ethyl ester

CAS: 141942-85-0

Formula: C₇H₁₁NO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 157.169

Ref: 10-F040195

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate

CAS: 141942-85-0

Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate is an asymmetric synthesis of D-(+)-glyceraldehyde. This compound is an acidic, high cholesterol substrate that binds to disaccharides and has hydroxyl groups. It has been shown to reduce low density lipoprotein levels in the blood by inhibiting the production of cholesterol in the liver. The reaction solution is immobilized on a solid support and is used for kinetic studies. Kinetic measurements were performed at different concentrations of hydrochloric acid and immobilized cells as a function of time. The reaction yield was determined using UV absorbance at 275 nm, which was plotted against time.

Purity: Min. 95%

Ref: 3D-FE38080