CAS 14197-60-5

Ginsenoside Rg3

Description:

Ginsenoside Rg3 is a natural compound classified as a triterpenoid saponin, primarily found in ginseng, particularly in Panax ginseng. It is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and anticancer effects. Ginsenoside Rg3 exists in two isomeric forms, Rg3(S) and Rg3(R), which may exhibit different biological activities. The compound has a complex molecular structure characterized by a steroid-like backbone with multiple hydroxyl groups, contributing to its solubility and reactivity. Ginsenoside Rg3 is often studied for its role in enhancing immune function and its potential neuroprotective effects. Additionally, it has been investigated for its ability to modulate various signaling pathways, making it a subject of interest in both traditional medicine and modern pharmacology. Its safety profile and therapeutic potential continue to be explored in clinical and preclinical studies, highlighting its relevance in health and wellness.

Formula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1

InChI key: InChIKey=RWXIFXNRCLMQCD-JBVRGBGGSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]

Synonyms:

• (20S)-Propanaxadiol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
• (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
• (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
• 20(R)-Propanaxadiol
• 20(S)-Ginsenoside-Rg3
• 20(S)-Ginsenoside-Rg₃
• 20(S)-Rg3
• 20S-Ginsenoside Rg3
• 3-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranosyldammar-24-ene-3β,12β,20S-triol
• Beta-D-Glucopyranoside,(3-Beta,12-Beta)-12,20-Dihydroxydammar-24-En-3-Yl2-O-B
• Dammar-24-Ene-12-Beta,20-Diol,3-Beta-((2-O-Beta-D-Glucopyranosyl-Beta-D-Gluc
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl)oxy]-
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Eta-D-Glucopyranosyl-
• Ginsenoside 20-Rg3
• Ginsenoside Rg3s
• Ginsenoside Rg₃
• Opyransoyl)Oxy)-
• S-Ginsenoside Rg₃
• beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-
• Dammarane, β-D-glucopyranoside deriv.
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

Formula: C₄₂H₇₂O₁₃

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 785.03

Ref: 3B-G0568

Ginsenoside Rg3

CAS: 14197-60-5

Ginsenoside Rg3 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₂H₇₂O₁₃

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 785.03

Ref: 11-0152S

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

20(S)-Ginsenoside Rg3

Purity: ≥98%

Molecular weight: 785.01g/mol

Ref: 54-BUP13475

Ginsenoside Rg3

CAS: 14197-60-5

Ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells, and the mechanism of their antimetastatic effect is related to inhibition of the adhesion and invasion of tumor cells, and also to anti-angiogenesis activity.

Formula: C₄₂H₇₂O₁₃

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 785.025

Ref: BP-BP0666

Ginsenoside Rg3

CAS: 14197-60-5

Formula: C₄₂H₇₂O₁₃

Molecular weight: 785.03

Ref: 4Z-G-157004

Ginsenoside Rg3-d6

CAS: 14197-60-5

Formula: C₄₂H₆₆D₆O₁₃

Molecular weight: 791.06

Ref: 4Z-G-157008

Ginsenoside Rg3

CAS: 14197-60-5

Formula: C₄₂H₇₂O₁₃

Purity: ≥ 98.0%

Color and Shape: White to beige powder

Molecular weight: 785.01

Ref: 7W-GC4250

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.

Formula: C₄₂H₇₂O₁₃

Purity: 98.11% - 99.93%

Color and Shape: Solid

Molecular weight: 785.01

Ref: TM-T3402

Ginsenoside rg3

CAS: 14197-60-5

Natural glycoside

Formula: C₄₂H₇₂O₁₃

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 785.03

Ref: 5G-89681

Ginsenoside Rg3

Controlled Product

CAS: 14197-60-5

Applications Ginsenoside Rg3 shows a synergistic antitumor effect with cisplatin in cisplatin-resistant bladder tumor cell lines and is considered to be an anti-tumor agent.
References Lee, Y; et al.: Onc. Rep., 32, 1803 (2014); Ge, X. et al.: J. Int. Med. Res., 42, 628 (2014)

Formula: C₄₂H₇₂O₁₃

Color and Shape: Neat

Molecular weight: 785.01

Ref: TR-G387590

(20S)-Ginsenoside Rg3

CAS: 14197-60-5

(20S)-Ginsenoside Rg3 is a bioactive saponin compound derived from the root of Panax ginseng. It is a naturally occurring component in ginseng, a traditional medicinal plant extensively studied for its diverse health benefits. The mode of action of (20S)-Ginsenoside Rg3 primarily involves the modulation of cellular pathways, such as the inhibition of tumor growth through apoptosis induction and anti-angiogenic effects. Additionally, it interacts with various signaling molecules, leading to its anti-inflammatory, antioxidant, and neuroprotective activities.

Formula: C₄₂H₇₂O₁₃

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 785.01 g/mol

Ref: 3D-OG09291