CAS 141977-79-9

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum

Description:

The chemical substance known as "(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)platinum" with CAS number 141977-79-9 is a platinum complex that features a chiral cyclohexanediamine ligand. This compound is characterized by its coordination of platinum to two tetradecanoate (fatty acid) ligands, which can influence its solubility and biological activity. The presence of the cyclohexanediamine moiety introduces chirality, potentially affecting the compound's interaction with biological systems and its pharmacological properties. Platinum complexes are often studied for their anticancer properties, as they can interact with DNA and inhibit cell division. The long-chain tetradecanoate ligands may enhance lipophilicity, impacting the compound's distribution in biological environments. Overall, this substance exemplifies the intersection of coordination chemistry and medicinal chemistry, with potential applications in targeted drug delivery and cancer therapy. Further studies would be necessary to elucidate its specific biological activity and therapeutic potential.

Formula: C₃₄H₆₈N₂O₄Pt

InChI: InChI=1S/2C14H28O2.C6H14N2.Pt/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;7-5-3-1-2-4-6(5)8;/h2*2-13H2,1H3,(H,15,16);5-6H,1-4,7-8H2;/q;;;+2/p-2/t;;5-,6-;/m..1./s1

InChI key: InChIKey=BGIHRZPJIYJKAZ-BLUNCNMSSA-L

SMILES: [O-](C(CCCCCCCCCCCCC)=O)[Pt+2]1([O-]C(CCCCCCCCCCCCC)=O)[NH2][C@]2([C@]([NH2]1)(CCCC2)[H])[H]

Synonyms:

• (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN¹,κN²]bis(tetradecanoato-κO)platinum
• Cyclohexane-(1R,2R)-diamineplatinum(II) dimyristate
• DACHPt(II)(Myr)2
• Dachpm
• Miripla
• Miriplatin
• Platinum, (1,2-cyclohexanediamine-N,N′)bis(tetradecanoato-O)-, [SP-4-2-(1R-trans)]-
• Platinum, (1,2-cyclohexanediamine-κN,κN′)bis(tetradecanoato-κO)-, [SP-4-2-[1R-(trans)]]-
• Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN,κN′]bis(tetradecanoato-κO)-, (SP-4-2)-
• Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN¹,κN²]bis(tetradecanoato-κO)-, (SP-4-2)-
• Sm-11355
• Smp-11355
• [(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum
• Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN1,κN2]bis(tetradecanoato-κO)-, (SP-4-2)-

Miriplatin

CAS: 141977-79-9

Miriplatin

Purity: ≥95%

Molecular weight: 763.99g/mol

Ref: 54-BUP11256

Miriplatin

CAS: 141977-79-9

Formula: C₃₄H₆₈N₂O₄Pt

Molecular weight: 764.01

Ref: 4Z-M-108015

Miriplatin

CAS: 141977-79-9

Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).

Formula: C₃₄H₆₈N₂O₄Pt

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 763.99

Ref: TM-T4368

Miriplatin

CAS: 141977-79-9

Formula: C₃₄H₆₈N₂O₄Pt

Purity: 98%

Color and Shape: Solid

Molecular weight: 763.9927

Ref: IN-DA009CDA