Description:Hexanoyl chloride, also known as caproyl chloride, is an acyl chloride derived from hexanoic acid. It is characterized by its molecular formula C6H11ClO and a carbon chain length of six carbon atoms. This colorless to pale yellow liquid has a pungent odor typical of acyl chlorides and is highly reactive, particularly with water, alcohols, and amines, leading to the formation of corresponding acids and esters. Hexanoyl chloride is soluble in organic solvents such as ether and chloroform but reacts vigorously with moisture, producing hydrochloric acid and hexanoic acid. It is commonly used in organic synthesis, particularly in the preparation of hexanoyl derivatives and as an acylating agent in various chemical reactions. Due to its reactivity, it should be handled with care, using appropriate safety measures to avoid exposure, as it can cause severe irritation to the skin, eyes, and respiratory tract. Proper storage in a cool, dry place away from moisture is essential to maintain its stability.
Hexanoyl chloride has been used in the synthesis of (±)-7-butyl-6,8-dihydroxy-3-pentyl-3,4-dihydroisochromen-1-one, 14-methyl-1-octadecene. It is used as …
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