2-Pyrimidinesulfonamide, also known by its CAS number 142047-90-3, is a chemical compound characterized by the presence of a pyrimidine ring substituted with a sulfonamide group. This compound typically exhibits properties associated with both heterocyclic compounds and sulfonamides, including potential biological activity. It is often utilized in medicinal chemistry due to its ability to interact with various biological targets, making it of interest in drug development. The sulfonamide moiety contributes to its solubility and reactivity, while the pyrimidine ring can participate in hydrogen bonding and π-π interactions. 2-Pyrimidinesulfonamide may also exhibit antimicrobial properties, similar to other sulfonamide derivatives, and can be involved in various synthetic pathways in organic chemistry. Its stability, solubility, and reactivity can vary depending on the specific conditions and solvents used. Overall, this compound represents a versatile structure with potential applications in pharmaceuticals and biochemistry.

2-Pyrimidinesulfonamide(9CI)

142047-90-3: 2-Pyrimidinesulfonamide, also known by its CAS number 142047-90-3, is a chemical compound characterized by the presence of a pyrimidine ring substituted with a sulfonamide group. This compound typically exhibits properties associated with both heterocyclic compounds and sulfonamides, including potential biological activity. It is often utilized in medicinal chemistry due to its ability to interact with various biological targets, making it of interest in drug development. The sulfonamide moiety contributes to its solubility and reactivity, while the pyrimidine ring can participate in hydrogen bonding and π-π interactions. 2-Pyrimidinesulfonamide may also exhibit antimicrobial properties, similar to other sulfonamide derivatives, and can be involved in various synthetic pathways in organic chemistry. Its stability, solubility, and reactivity can vary depending on the specific conditions and solvents used. Overall, this compound represents a versatile structure with potential applications in pharmaceuticals and biochemistry.

2-Pyrimidinesulfonamide

Pyrimidine-2-sulfonamide

<p>Pyrimidine-2-sulfonamide is a sulfonamide that inhibits the bcr-abl kinase and is used to treat chronic myelogenous leukemia (CML). It has been shown to inhibit the growth of cancer cells in vitro. The compound was found to be effective in Sprague-Dawley rats with CML, but not in CD1 mice. This drug also has an effect on the production of chemokines, which are important for the migration of immune cells. Pyrimidine-2-sulfonamide may act as a chemoattractant by binding to G protein coupled receptors, such as CXCR4 and CXCR3.</p>

CAS 142047-90-3

2-Pyrimidinesulfonamide(9CI)

2-Pyrimidinesulfonamide

Ref: IN-DA001HML

Pyrimidine-2-sulfonamide

Ref: 54-OR1061996

Pyrimidine-2-sulfonamide

Ref: 3D-SFA04790