CAS 1421-65-4

L-3,4-dihydroxyphenylalanine methyl*ester hydroch

Description:

L-3,4-dihydroxyphenylalanine methyl ester hydrochloride, commonly referred to as L-DOPA methyl ester, is a derivative of the amino acid L-DOPA, which is a precursor to neurotransmitters such as dopamine. This compound is characterized by its hydroxyl groups on the benzene ring, which contribute to its reactivity and solubility in polar solvents. The presence of the methyl ester group enhances its lipophilicity compared to L-DOPA, potentially affecting its absorption and bioavailability. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for various pharmaceutical applications. L-DOPA and its derivatives are primarily studied for their role in treating conditions such as Parkinson's disease, where dopamine deficiency is a significant concern. The compound's pharmacological properties, including its ability to cross the blood-brain barrier, make it a critical focus in neuropharmacology. Additionally, its synthesis and characterization are of interest in medicinal chemistry for developing new therapeutic agents.

Formula: C₁₀H₁₄ClNO₄

InChI: InChI=1/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H

InChI key: InChIKey=WFGNJLMSYIJWII-FJXQXJEOSA-N

SMILES: C([C@@H](C(OC)=O)N)C1=CC(O)=C(O)C=C1.Cl

Synonyms:

• (S)-Dopa methyl ester hydrochloride
• (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
• 3,4-Dihydroxyphenyl-<span class="text-smallcaps">L</span>-alanine methyl ester hydrochloride
• 3-Hydroxy-<span class="text-smallcaps">L</span>-tyrosine methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Dopa methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, <span class="text-smallcaps">L</span>-
• L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride
• L-DOPA Me ester hydrochloride
• Levodopa methyl ester hydrochloride
• Methyl 3-Hydroxytyrosinate
• Methyl 3-Hydroxytyrosinate Hydrochloride (1:1)
• Methyl <span class="text-smallcaps">L</span>-3-(3,4-dihydroxyphenyl)alaninate hydrochloride
• St 41769
• methyl 3-hydroxy-L-tyrosinate hydrochloride (1:1)
• L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride
• L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)
• 3,4-Dihydroxyphenyl-L-alanine methyl ester hydrochloride
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, L-
• L-3,4-Dihydroxyphenylalanine methyl ester
• Methyl L-3-(3,4-dihydroxyphenyl)alaninate hydrochloride
• -3,4-Dihydroxyphenylalanine methyl ester hydrochloride
• Dihydroxyphenylalanine Methyl ester hydrochloride
• TIANFUCHEM--1421-65-4--High purity L-3,4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE in stock
• Nsc295453
• LevoMet Hydrochloride
• L-3,4-DIHYDROXYPHENYLALANINE METHYLESTER HYDROCHLO
• 3-Hydroxy-L-tyrosine Methyl Ester Hydrochloride
• L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride,>95%
• Melevodopa Hydrochloride
• H-PHE(3,4-DI-HYDROXY)-OME HCL
• METHYL L-DOPA HYDROCHLORIDE
• 3,4-
• Methyl 3-Hydroxy-L-tyrosine Hydrochloride
• [(2S)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]azanium
• 3-hydroxy- L-Tyrosine methyl ester, hydrochloride (1:1)
• Levodopa Impurity 10
• Melevodopa
• L-DOPA Methyl Ester Hydrochloride
• -Methyl 2-amino-3-(3,4-dihydroxyphenyl)
• methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
• H-TYR(3-HYDROXY)-OME HCL
• methyldopa hydrochloride
• 3-(3,4-Dihydroxyphenyl)alanine Methyl Ester Hydrochloride
• 2-Amino-3-(3,4-dihydroxyphenyl)-propanoic acid methylester hydrochloride
• L
• 4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE
• 3,4-DIHYDROXY PHENYLALANINE METHYL ESTER HYDROCHLORIDE
• -
• 3,4-Dihydroxy-L-phenylalanine Methyl Ester Hydrochloride
• (S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid hydrochloride
• L-3,4-dihydroxyphenylalanine methyl*ester hydroch
• Dopamine, methyl ester

L-Dopa Methyl Ester Hydrochloride

CAS: 1421-65-4

Formula: C₁₀H₁₃NO₄·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 247.68

Ref: 3B-D6060

L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)

CAS: 1421-65-4

Formula: C₁₀H₁₄ClNO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 247.6755

Ref: IN-DA001HT2

L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride

CAS: 1421-65-4

L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride

Purity: 98%

Molecular weight: 247.68g/mol

Ref: 54-OR1013624

L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride

CAS: 1421-65-4

Formula: C₁₀H₁₃NO₄·HCl

Purity: ≥ 98.0%

Color and Shape: Conflicting attributes defined

Molecular weight: 247.68

Ref: 7W-GK2381

Levodopa Methyl Ester Hydrochloride

CAS: 1421-65-4

Color and Shape: Neat

Ref: 86-MM0262.18

L-DOPA methyl ester (hydrochloride)

CAS: 1421-65-4

L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.

Formula: C₁₀H₁₄ClNO₄

Purity: 98.69% - 99.81%

Color and Shape: White Solid

Molecular weight: 247.675

Ref: TM-T7654

L-DOPA Methyl Ester Hydrochloride

Controlled Product

CAS: 1421-65-4

Applications L-DOPA Methyl Ester Hydrochloride is a selective Dopamine D1 receptor agonist (1,2,3).
References (1) Astradsson, A., et al.: Neurobiol. Dis., 35, 348 (2009)(2) Garcia-Molina, F., et al.: J. Agric. Food Chem., 57, 1143 (2009) (3) Giorgioni, G., et al.: Bioorg. Med. Chem., 18, 1834 (2010)

Formula: C₁₀H₁₃NO₄·ClH

Color and Shape: Neat

Molecular weight: 247.68

Ref: TR-D533770

L-DOPA methyl ester hydrochloride

Controlled Product

CAS: 1421-65-4

L-DOPA methyl ester hydrochloride is a form of L-dopa that is used to treat Parkinson's disease. It is a prodrug of L-dopa, which has been shown to have a pharmacokinetic profile similar to that of levodopa. L-DOPA methyl ester hydrochloride is administered orally and is released slowly into the blood stream over time. This drug has been shown to interact with other drugs, such as antidepressants and antipsychotics, through its effects on neurotransmitters. In addition, this drug may cause locomotor activity in animals and can cause an increase in levels of dehydroascorbic acid in patients with chronic oral administration.

Formula: C₁₀H₁₃NO₄•HCl

Purity: Min. 96 Area-%

Color and Shape: Powder

Molecular weight: 247.68 g/mol

Ref: 3D-FD22596

(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride

CAS: 1421-65-4

Formula: C₁₀H₁₄ClNO₄

Purity: 98%

Color and Shape: Liquid, No data available.

Molecular weight: 247.68

Ref: 10-F223023