CAS 1421373-66-1

2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-, methanesulfonate (1:1)

Description:

2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-, methanesulfonate (1:1) is a complex organic compound characterized by its multi-functional structure, which includes an amide group, a methanesulfonate moiety, and various aromatic and heterocyclic components. This compound features a propenamide backbone, indicating potential reactivity in polymerization or other chemical transformations. The presence of dimethylamino and methoxy groups suggests it may exhibit basic properties and potential for hydrogen bonding, influencing its solubility and interaction with biological systems. The indole and pyrimidine rings contribute to its potential pharmacological activity, making it a candidate for research in medicinal chemistry. Its methanesulfonate salt form enhances its solubility in polar solvents, which is advantageous for formulation in pharmaceutical applications. Overall, this compound's intricate structure and functional groups suggest diverse applications, particularly in drug development and biochemical research.

Formula: C₂₈H₃₃N₇O₂·CH₄O₃S

InChI: InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)

InChI key: InChIKey=FUKSNUHSJBTCFJ-UHFFFAOYSA-N

SMILES: CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3.S(C)(=O)(=O)O

Synonyms:

• 2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-, methanesulfonate (1:1)
• N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1)
• Osimertinib mesylate
• AZD-9291 mesylate
• AZD 9291 mesylate

Osimertinib Mesylate

CAS: 1421373-66-1

Osimertinib Mesylate

Purity: 99%

Molecular weight: 595.71g/mol

Ref: 54-OR1027332

Osimertinib mesylate

CAS: 1421373-66-1

Osimertinib mesylate

Purity: ≥98%

Molecular weight: 595.71g/mol

Ref: 54-BUP17102

Osimertinib Mesylate

CAS: 1421373-66-1

Formula: C₂₈H₃₃N₇O₂·CH₄O₃S

Molecular weight: 499.62 96.10

Ref: 4Z-A-194063

Osimertinib mesylate

CAS: 1421373-66-1

Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.

Formula: C₂₉H₃₇N₇O₅S

Purity: 99.46% - >99.99%

Color and Shape: Solid

Molecular weight: 595.71

Ref: TM-T3634

AZD-9291 Mesylate

Controlled Product

CAS: 1421373-66-1

Applications AZD-9291 Mesylate is a potent and selective epidermal growth factor receptor (EGFR) inhibitor.
References Finlay, M.; et al.: J. Med. Chem., 57, 8249 (2014)

Formula: C₂₈H₃₃N₇O₂·CH₄O₃S

Color and Shape: Neat

Molecular weight: 595.71

Ref: TR-A808205

AZD 9291 mesylate

CAS: 1421373-66-1

Inhibitor of EGFR transmembrane receptor

Formula: C₂₈H₃₃N₇O₂·CH₄O₃S

Purity: Min. 98 Area-%

Color and Shape: White To Yellow To Brown Solid

Ref: 3D-FD146297