CAS 1421683-12-6

N-[(4S)-1-Acetyl-1,2,3,4-tetrahydro-4-methyl-4-phenyl-6-quinolinyl]-3-(trifluoromethyl)benzenepropanamide

Description:

N-[(4S)-1-Acetyl-1,2,3,4-tetrahydro-4-methyl-4-phenyl-6-quinolinyl]-3-(trifluoromethyl)benzenepropanamide is a complex organic compound characterized by its unique structural features, including a quinoline moiety and a trifluoromethyl group. The presence of the tetrahydroquinoline structure suggests potential biological activity, as many compounds with similar frameworks exhibit pharmacological properties. The trifluoromethyl group is known to enhance lipophilicity and metabolic stability, which can influence the compound's bioavailability and interaction with biological targets. This compound may be of interest in medicinal chemistry, particularly in the development of new therapeutic agents. Its synthesis likely involves multi-step organic reactions, and its characterization would typically include techniques such as NMR, mass spectrometry, and IR spectroscopy to confirm its structure and purity. Additionally, understanding its solubility, stability, and reactivity under various conditions would be essential for potential applications in drug development or chemical research.

Formula: C₂₈H₂₇F₃N₂O₂

Synonyms:

• N-[(4S)-1-Acetyl-1,2,3,4-tetrahydro-4-methyl-4-phenyl-6-quinolinyl]-3-(trifluoromethyl)benzenepropanamide

(S)-N-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydroquinolin-6-yl)-3-(3-(trifluoromethyl)phenyl)propanamide

CAS: 1421683-12-6

(S)-N-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydroquinolin-6-yl)-3-(3-(trifluoromethyl)phenyl)propanamide

Purity: 98%

Molecular weight: 480.53g/mol

Ref: 54-PC1007692

Org 274179-0

CAS: 1421683-12-6

Org 274179-0 is an effective allosteric antagonist of the thyroid-stimulating hormone (TSH) receptor, with an IC50 in the nanomolar range. It fully inhibits TSH (and TSI)-mediated activation of the TSH receptor with minimal impact on the efficacy of TSH. This compound can be utilized in studies of Graves' disease (GD).

Formula: C₂₈H₂₇F₃N₂O₂

Color and Shape: Solid

Molecular weight: 480.521

Ref: TM-T204377