CAS 1422-07-7

codeine hydrochloride

Description:

Codeine hydrochloride is an opiate used primarily for its analgesic, antitussive, and antidiarrheal properties. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. As a prodrug, codeine is metabolized in the liver to morphine, which contributes to its pain-relieving effects. Its chemical structure features a phenanthrene core with a methoxy group and a hydroxyl group, which are responsible for its pharmacological activity. Codeine hydrochloride is typically administered in oral form, and its effects can vary based on individual metabolism and dosage. While it is effective for managing mild to moderate pain, it also carries a risk of dependence and side effects, including drowsiness, constipation, and respiratory depression. Due to its potential for abuse, codeine is classified as a controlled substance in many jurisdictions, necessitating careful regulation and monitoring in medical use.

Formula: C₁₈H₂₂ClNO₃

InChI: InChI=1/C18H21NO3.ClH/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;/h3-6,11-13,17,20H,7-9H2,1-2H3;1H/t11-,12+,13-,17?,18-;/m0./s1

InChI key: InChIKey=NUXLENPAZQNFAM-FFHNEAJVSA-N

SMILES: O[C@@H]1[C@]2([C@]34C=5C(O2)=C(OC)C=CC5C[C@]([C@@]3(C=C1)[H])(N(C)CC4)[H])[H].Cl

Synonyms:

• (6Alpha)-3-Methoxy-17-Methyl-7,8-Didehydro-4,5-Epoxymorphinan-17-Ium-6-Ol Chloride
• Codeine HCl
• Codeinium chloride
• Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-, hydrochloride
• Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, hydrochloride (1:1), (5α,6α)-
• Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, hydrochloride, (5α,6α)-
• Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methyl-, hydrochloride
• Codeine hydrochloride
• Codeinum Hcl
• CODEINE HYDROCHLORIDE DIHYDRATE
• NUXLENPAZQNFAM-FFHNEAJVSA-N

Codeine.HCl, 1mg/ml in Methanol (as free base)

Controlled Product

CAS: 1422-07-7

Color and Shape: Single Solution

Ref: LP-C-69-HC-1LM

Codeine.HCl

Controlled Product

CAS: 1422-07-7

Color and Shape: Neat

Ref: LP-C-69-HC-10

Codeine hydrochloride

Controlled Product

CAS: 1422-07-7

Codeine is a natural product that is extracted from the opium poppy. It can be found as the primary or secondary metabolite of other plants and has been shown to have bioactive properties. Codeine hydrochloride is used as a reference material for research and development in areas such as pharmacology, toxicology, biology, medicine, and biochemistry. HPLC standards are made by extracting codeine from opium with ethanol in order to purify it. The purity of these standards is verified by HPLC analysis. Quality control includes screening for impurities such as glucose and acetone, which may be present in codeine extracts due to the presence of other plants in the sample. Secondary metabolites are also screened for using analytical methods such as gas chromatography-mass spectrometry (GC-MS) or nuclear magnetic resonance (NMR). CAS No. 1422-07-7 is an identifier given to all substances that have been assigned a unique number by the Chemical Abstracts Service registry system.

Formula: C₁₈H₂₂ClNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 335.83 g/mol

Ref: 3D-FC178719

Codeine Hydrochloride

Controlled Product

CAS: 1422-07-7

Formula: C₁₈H₂₁NO₃·ClH

Color and Shape: White To Off-White

Molecular weight: 335.83

Ref: TR-C634078

Codeine hydrochloride

Controlled Product

CAS: 1422-07-7

Codeine hydrochloride

Color and Shape: Off White Powder

Ref: 47-514