CAS 142217-77-4: (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

Description: The chemical substance with the name "(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol" and CAS number "142217-77-4" is a complex organic compound characterized by its multi-functional groups and stereochemistry. It features a cyclopentanol core, which is a five-membered cyclic alcohol, and is substituted with multiple benzyloxy groups, enhancing its lipophilicity and potential biological activity. The presence of an amino group and a purine derivative suggests that this compound may exhibit properties relevant to nucleic acid chemistry or serve as a potential pharmaceutical agent. The specific stereochemistry indicated by the (1S,2S,3S,5S) configuration implies that the compound has defined spatial arrangements, which can significantly influence its reactivity and interaction with biological targets. Overall, this compound's structural complexity and functional groups suggest potential applications in medicinal chemistry, particularly in the development of therapeutics targeting nucleic acid-related processes.

Formula: C₃₂H₃₃N₅O₄

InChI: InChI=1/C32H33N5O4/c33-32-35-30-28(31(36-32)41-19-24-14-8-3-9-15-24)34-21-37(30)26-16-27(40-18-23-12-6-2-7-13-23)25(29(26)38)20-39-17-22-10-4-1-5-11-22/h1-15,21,25-27,29,38H,16-20H2,(H2,33,35,36)/t25-,26+,27+,29+/m1/s1

Synonyms:

• (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cydopentanol
• Entecavir intermediate N4
• (1S,2S,3S,5S)-5-(2-amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((4-methylbenzyloxy)methyl)cyclopentanol
• Ent-4
• Intermediate of Entecavir 2
• (1S,2S,3S,5S)-5-(2-amino-6-(benzyloxyl)-9H-purin-9yl)-3-(benzyloxymethyl)cyclopentanol
• (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl) cyclopentanol

Cyclopentanol, 5-[2-amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S)-

CAS: 142217-77-4

• Formula: C₃₂H₃₃N₅O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 551.6355

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

CAS: 142217-77-4

• Purity: 97%
• Molecular weight: 551.64697265625

Entecavir Impurity 36

CAS: 142217-77-4

• Formula: C₃₂H₃₃N₅O₄
• Molecular weight: 551.65

(2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol

CAS: 142217-77-4

Applications (2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol is an intermediate in the preparation of ent-Entecavir (E558905).

• Formula: C₃₂H₃₃N₅O₄
• Color and Shape: Neat
• Molecular weight: 551.635

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

CAS: 142217-77-4

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol is a synthetic compound that is used to treat patients with chronic myeloid leukemia. …

• Formula: C₃₂H₃₃N₅O₄
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 551.64 g/mol