CAS 142227-49-4: (R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL

Description: (R)-(+)-4'-Hydroxyphenyl-carvedilol is a chiral compound that belongs to the class of beta-blockers, which are primarily used in the treatment of cardiovascular conditions. This substance is a derivative of carvedilol, known for its dual action as both a beta-adrenergic antagonist and an alpha-1 adrenergic antagonist. The (R)-enantiomer is particularly significant due to its enhanced pharmacological activity compared to its (S)-counterpart. The presence of the hydroxyl group on the phenyl ring contributes to its solubility and interaction with biological targets. This compound exhibits properties such as antioxidant activity, which may provide additional therapeutic benefits. Its stereochemistry plays a crucial role in its efficacy and safety profile, making it important for drug development and clinical applications. As with many beta-blockers, it may have side effects, including fatigue and dizziness, and its use should be monitored in patients with specific health conditions. Overall, (R)-(+)-4'-hydroxyphenyl-carvedilol represents a significant advancement in cardiovascular pharmacotherapy.

Formula: C₂₄H₂₆N₂O₅

Synonyms:

• (S)-(-)-4'-Hydroxyphenyl-Carvedilol
• (R)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
• (R)-4-Hydroxycarvedilol
• (R)-Bm 140686
• (R)-Bm 14686
• (S)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
• (S)-4-Hydroxycarvedilol

Phenol, 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-

CAS: 142227-49-4

• Formula: C₂₄H₂₆N₂O₅
• Color and Shape: Solid
• Molecular weight: 422.4736

4'-Hydroxyphenyl Carvedilol

CAS: 142227-49-4

• Formula: C₂₄H₂₆N₂O₅
• Color and Shape: Brown Solid
• Molecular weight: 422.48

Carvedilol metabolite 4-Hydroxyphenyl Carvedilol

CAS: 142227-49-4

4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker.

• Formula: C₂₄H₂₆N₂O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 422.47

4’-Hydroxyphenyl Carvedilol

CAS: 142227-49-4

Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension. References …

• Formula: C₂₄H₂₆N₂O₅
• Color and Shape: Off White Solid
• Molecular weight: 422.47

4’-Hydroxyphenyl Carvedilol Hydrochloride

CAS: 142227-49-4

• Formula: C₂₄H₂₆N₂O₅·HCl
• Color and Shape: Neat
• Molecular weight: 458.935

4'-Hydroxyphenyl carvedilol

CAS: 142227-49-4

4'-Hydroxyphenyl carvedilol is a metabolite of carvedilol, which is an inhibitor of the enzyme catechol-O-methyltransferase. …

• Formula: C₂₄H₂₆N₂O₅
• Purity: Min. 95%
• Molecular weight: 422.47 g/mol