CAS 142227-51-8
:5'-HYDROXYPHENYL CARVEDILOL
Description:
5'-Hydroxyphenyl carvedilol is a derivative of carvedilol, which is a non-selective beta-blocker and alpha-1 blocker used primarily in the treatment of hypertension and heart failure. This compound features a hydroxyl group at the 5' position of the phenyl ring, which may influence its pharmacological properties and interactions. The presence of the hydroxyl group can enhance solubility and potentially alter the compound's binding affinity to adrenergic receptors. As a chemical entity, it is characterized by its molecular structure, which includes a chiral center, contributing to its stereoisomerism. The compound is typically studied for its potential therapeutic effects, including antioxidant properties and its role in cardiovascular health. Its CAS number, 142227-51-8, allows for precise identification in chemical databases. Overall, 5'-hydroxyphenyl carvedilol represents an interesting area of research in medicinal chemistry, particularly in the development of more effective cardiovascular agents with improved safety profiles.
Formula:C24H26N2O5
InChI:InChI=1/C24H26N2O5/c1-29-21-10-9-16(27)13-23(21)30-12-11-25-14-17(28)15-31-22-8-4-7-20-24(22)18-5-2-3-6-19(18)26-20/h2-10,13,17,25-28H,11-12,14-15H2,1H3
SMILES:COc1ccc(cc1OCCNCC(COc1cccc2c1c1ccccc1[nH]2)O)O
Synonyms:- 3-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxyphenol
- 5-Hydroxycarvedilol
- Bm 140830
- M4
- 5'-HYDROXYPHENYL CARVEDILOL
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Found 4 products.
Phenol, 3-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-4-methoxy-
CAS:Formula:C24H26N2O5Color and Shape:SolidMolecular weight:422.47365'-Hydroxyphenyl Carvedilol
CAS:Formula:C24H26N2O5Color and Shape:Off-White SolidMolecular weight:422.485’-Hydroxyphenyl Carvedilol
CAS:<p>Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formula:C24H26N2O5Color and Shape:NeatMolecular weight:422.47



