CAS 1422359-85-0

Fumonisin B3

Description:

Fumonisin B3 is a mycotoxin produced by certain species of fungi, particularly Fusarium species, which are commonly found on corn and other cereal grains. It is part of the fumonisin family, which includes several related compounds known for their potential health risks. Fumonisin B3 is characterized by its structural features, including a long carbon chain and multiple functional groups, which contribute to its biological activity. This compound is primarily recognized for its ability to disrupt sphingolipid metabolism, leading to various toxicological effects, including hepatotoxicity and nephrotoxicity in animals. It has been studied for its potential role in human health issues, particularly in relation to certain cancers and neural tube defects. Fumonisin B3 is typically analyzed in food and feed products to assess contamination levels, as regulatory agencies monitor mycotoxin levels to ensure food safety. Its presence in agricultural products raises concerns about food safety and public health, necessitating ongoing research into its effects and mitigation strategies.

Formula: C₃₄H₅₉NO₁₄

InChI: InChI=1S/C34H59NO14/c1-5-6-11-21(3)32(49-31(43)19-24(34(46)47)17-29(40)41)27(48-30(42)18-23(33(44)45)16-28(38)39)15-20(2)14-25(36)12-9-7-8-10-13-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)/t20-,21+,22-,23+,24+,25+,26-,27-,32+/m0/s1

InChI key: InChIKey=CPCRJSQNWHCGOP-STOIETHLSA-N

SMILES: [C@@H]([C@@H](OC(C[C@@H](CC(O)=O)C(O)=O)=O)C[C@H](C[C@@H](CCCCCC[C@@H]([C@H](C)N)O)O)C)(OC(C[C@@H](CC(O)=O)C(O)=O)=O)[C@@H](CCCC)C

Synonyms:

• 1,2,3-Propanetricarboxylic acid, 1,1′-[(1S,2R)-1-[(2S,4R,11S,12S)-12-amino-4,11-dihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester, (2R,2′R)-
• Fumonisin B3
• FB3

1,2,3-Propanetricarboxylic acid, 1,1'-[(1S,2R)-1-[(2S,4R,11S,12S)-12-amino-4,11-dihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester, (2R,2'R)-

CAS: 1422359-85-0

Formula: C₃₄H₅₉NO₁₄

Color and Shape: Solid

Molecular weight: 705.8306

Ref: IN-DA0011T7

Fumonisin B3

CAS: 1422359-85-0

Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins.

Formula: C₃₄H₅₉NO₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 705.83

Ref: TM-T19330

Fumonisin B3 from Fusarium moniliforme

CAS: 1422359-85-0

Fumonisin B3 from Fusarium moniliforme

Formula: C₃₄H₅₉NO₁₄

Purity: By hplc: 100% (Typical Value in Batch COA)

Color and Shape: white lyophilizate solid

Molecular weight: 705.83g/mol

Ref: 54-BIF1008

Fumonisin B3 50 µg/mL in Acetonitrile/Water

Controlled Product

CAS: 1422359-85-0

Formula: C₃₄H₅₉NO₁₄

Color and Shape: Single Solution

Molecular weight: 705.83

Ref: 04-A13955910WL-50

Fumonisin B3 (>90%)

Controlled Product

CAS: 1422359-85-0

Formula: C₃₄H₅₉NO₁₄

Purity: >90%

Color and Shape: Neat

Molecular weight: 705.83

Ref: TR-F862765

Fumonisin B3

CAS: 1422359-85-0

Fumonisin B3 is a mycotoxin compound, which is a secondary metabolite produced by molds, particularly those belonging to the Fusarium species. It is primarily found in cereal grains such as maize, where these fungi commonly thrive in specific environmental conditions. With a structure related to sphingoid bases, Fumonisin B3 interferes with sphingolipid metabolism by inhibiting the ceramide synthase enzyme. This disruption leads to the accumulation of sphinganine and a reduction in complex sphingolipids, affecting cell membrane integrity and signaling pathways.

Formula: C₃₄H₅₉NO₁₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 705.83 g/mol

Ref: 3D-BF162729

Fumonisin B3

CAS: 1422359-85-0

Formula: C₃₄H₅₉NO₁₄

Molecular weight: 705.84

Ref: 4Z-F-110002

Fumonisin B3

Controlled Product

CAS: 1422359-85-0

Stability Hygroscopic
Applications Fumonisin B3 is a mycotoxin present in corn. Fungal metabolite believed to cause leukoencephalomalacia in horses.
References Azcona-Olivera, J. et al.: J. Agric. Food Chem., 40, 531 (1992); Hopmans, E. et al.: J. Agric. Food Chem., 41, 1655 (1993); Monbaliu, S., et al.: J. Agric. Food Chem., 58, 10475 (2010), Klosowski, G., et al.: Biores. Technol., 101, 9723 (2010), Soerensen, L., et al.: Anal. Bioanal. Chem., 398, 1535 (2010),

Formula: C₃₄H₅₉NO₁₄

Color and Shape: Beige

Molecular weight: 705.83

Ref: TR-F862760