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CAS 142246-63-7

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5-fluorodeoxyuridine-ce*phosphoramidite for abi

Description:
5-Fluorodeoxyuridine-ce*phosphoramidite is a chemical compound primarily used in the field of molecular biology and biochemistry, particularly in the synthesis of oligonucleotides. This compound is a modified nucleoside analog of deoxyuridine, where the hydrogen atom at the 5-position of the uracil base is replaced by a fluorine atom, enhancing its stability and incorporation into DNA. The phosphoramidite moiety allows for efficient coupling during the solid-phase synthesis of DNA, making it a valuable reagent in the production of oligonucleotides for research and therapeutic applications. The presence of the fluorine atom can also impart unique properties, such as altered base pairing and increased resistance to enzymatic degradation. As a phosphoramidite, it is typically used in a protected form, which is activated during the synthesis process to facilitate the formation of phosphodiester bonds. Overall, 5-fluorodeoxyuridine-ce*phosphoramidite serves as a crucial tool in genetic engineering, antisense oligonucleotide development, and various applications in nucleic acid research.
Formula:C39H46FN4O8P
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