CAS 142326-59-8

7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone

Description:

7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone, with the CAS number 142326-59-8, is a synthetic organic compound characterized by its quinolinone core structure, which is a bicyclic compound featuring a fused benzene and pyridine ring. This compound exhibits a chloro substituent at the 7-position and a hydroxy group at the 4-position, contributing to its potential biological activity. The presence of a phenoxyphenyl group at the 3-position enhances its lipophilicity and may influence its interaction with biological targets. Typically, compounds of this class are investigated for their pharmacological properties, including antimicrobial and anticancer activities. The molecular structure suggests that it may participate in hydrogen bonding due to the hydroxyl group, which could affect its solubility and reactivity. Additionally, the chlorine atom may influence the electronic properties of the molecule, potentially enhancing its biological efficacy. Overall, this compound represents a class of heterocyclic compounds with diverse applications in medicinal chemistry.

Formula: C₂₁H₁₄ClNO₃

InChI: InChI=1S/C21H14ClNO3/c22-14-9-10-17-18(12-14)23-21(25)19(20(17)24)13-5-4-8-16(11-13)26-15-6-2-1-3-7-15/h1-12H,(H2,23,24,25)

InChI key: InChIKey=FLVRDMUHUXVRET-UHFFFAOYSA-N

SMILES: OC1=C(C2=CC(OC3=CC=CC=C3)=CC=C2)C(=O)NC=4C1=CC=C(Cl)C4

Synonyms:

• L 701324
• 7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone
• 2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-

L-701,324

CAS: 142326-59-8

Formula: C₂₁H₁₄ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 363.7938

Ref: IN-DA009CIR

L-701,324

CAS: 142326-59-8

Formula: C₂₁H₁₄ClNO₃

Molecular weight: 363.79

Ref: 7W-GK7740

L-701324

CAS: 142326-59-8

L-701324

Purity: ≥98%

Molecular weight: 363.79g/mol

Ref: 54-BUP13457

7-Chloro-4-Hydroxy-3-(3-Phenoxyphenyl)Quinolin-2(1H)-One

CAS: 142326-59-8

7-Chloro-4-Hydroxy-3-(3-Phenoxyphenyl)Quinolin-2(1H)-One

Purity: 98%

Molecular weight: 363.79g/mol

Ref: 54-OR1022879

L-701324

CAS: 142326-59-8

L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.

Formula: C₂₁H₁₄ClNO₃

Purity: 98.63% - >99.99%

Color and Shape: Solid

Molecular weight: 363.79

Ref: TM-T1909

L-701,324

Controlled Product

CAS: 142326-59-8

Formula: C₂₁H₁₄ClNO₃

Color and Shape: Neat

Molecular weight: 363.794

Ref: TR-L009510

L-701,324

CAS: 142326-59-8

L-701,324 is a selective antagonist of the response element-binding protein (REB). It prevents the transcription of the gene encoding this protein by binding to its DNA-binding site in the regulatory region of this gene. L-701,324 has been shown to have antagonistic effects on glutamate receptors and may be useful for treating neurodegenerative disorders. L-701,324 has also been shown to have anti-locomotor activity in animals and an interactive effect with other pharmacological agents. This drug has not yet been evaluated in humans.

Formula: C₂₁H₁₄ClNO₃

Purity: Min. 95%

Molecular weight: 363.79 g/mol

Ref: 3D-SFA32659