CAS 142340-99-6
:Adefovir dipivoxil
Description:
Adefovir dipivoxil is an antiviral medication primarily used in the treatment of chronic hepatitis B virus (HBV) infection. It is a prodrug of adefovir, which means it is converted into its active form in the body. The compound is characterized by its ability to inhibit viral DNA polymerase, thereby preventing the replication of the virus. Adefovir dipivoxil is typically administered orally and is known for its relatively low toxicity profile compared to other antiviral agents. Its chemical structure includes a phosphonate group, which contributes to its mechanism of action. The substance is soluble in water and exhibits stability under physiological conditions. Common side effects may include nephrotoxicity and gastrointestinal disturbances, necessitating monitoring of renal function during treatment. Adefovir dipivoxil is classified as a nucleoside analogue and is part of the antiviral drug class, making it an important option in the management of HBV, especially in patients who are resistant to other therapies.
Formula:C20H32N5O8P
InChI:InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)
InChI key:InChIKey=WOZSCQDILHKSGG-UHFFFAOYSA-N
SMILES:C(COCP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)N1C=2C(N=C1)=C(N)N=CN2
Synonyms:- 3-{[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}-8,8-dimethyl-3-oxido-7-oxo-2,4,6-trioxa-3lambda~5~-phosphanon-1-yl 2,2-dimethylpropanoate
- 9-[2-[Bis[(Pivaloyloxy)Methoxy]Phosphinyl]Methoxy]Ethyl]Adenine
- Adefovir Dipivoxl
- Adefovir Pivoxil
- Adefovir dipivoxil
- Gs 0840
- Hepsera
- Preveon
- Propanoic acid, 2,2-dimethyl-, 1,1′-[[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]phosphinylidene]bis(oxymethylene)] ester
- Propanoic acid, 2,2-dimethyl-, [[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]phosphinylidene]bis(oxymethylene) ester
- [2-(6-Aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
- See more synonyms
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Found 13 products.
Adefovir Dipivoxil
CAS:Formula:C20H32N5O8PPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:501.48Adefovir dipivoxil
CAS:Formula:C20H32N5O8PPurity:≥ 98.0%Color and Shape:White to almost white powder or crystalline powderMolecular weight:501.47Adefovir Dipivoxil
CAS:Formula:C20H32N5O8PColor and Shape:White To Off-White SolidMolecular weight:501.48Adefovir dipivoxil 100 µg/mL in Acetonitrile
CAS:Formula:C20H32N5O8PColor and Shape:Single SolutionMolecular weight:501.47Adefovir Dipivoxil
CAS:Controlled ProductFormula:C20H32N5O8PColor and Shape:NeatMolecular weight:501.47Adefovir dipivoxil
CAS:Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity againstFormula:C20H32N5O8PPurity:98% - 99.80%Color and Shape:It Has Broad-Spectrum Antiviral ActivityMolecular weight:501.47Adefovir dipivoxil
CAS:Controlled ProductApplications A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI).
References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010), Ming, X., et al.: Biochem. Pharmacol., 79, 455 (2010),Formula:C20H32N5O8PColor and Shape:NeatMolecular weight:501.47Adefovir dipivoxil - Bio-X ™
CAS:Adefovir is an antiviral acyclic nucleoside phosphonate (ANP) analogue that works by blocking reverse transcriptase. This drug is used to treat infections associated with Hepatitis B.Formula:C20H32N5O8PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:501.47 g/molAdefovir dipivoxil
CAS:Anti-viral; reverse transcriptase inhibitorFormula:C20H32N5O8PPurity:Min. 95%Color and Shape:White PowderMolecular weight:501.47 g/mol
