CAS 1424-27-7

Acetazolamide sodium

Description:

Acetazolamide sodium is a carbonic anhydrase inhibitor primarily used as a diuretic and in the treatment of conditions such as glaucoma, altitude sickness, and certain types of epilepsy. It is a white to off-white crystalline powder that is soluble in water, making it suitable for intravenous administration. The compound works by inhibiting the enzyme carbonic anhydrase, which plays a crucial role in the regulation of acid-base balance and fluid secretion in the body. This inhibition leads to increased bicarbonate and sodium excretion, resulting in a mild diuretic effect. Acetazolamide sodium is typically administered orally or intravenously, and its effects can be observed relatively quickly. Common side effects may include tingling sensations, electrolyte imbalances, and gastrointestinal disturbances. Due to its mechanism of action, it is also utilized in managing conditions related to fluid retention and certain metabolic disorders. As with any medication, it is essential to use acetazolamide sodium under medical supervision to monitor for potential adverse effects and interactions with other drugs.

Formula: C₄H₆N₄O₃S₂·Na

InChI: InChI=1S/C4H6N4O3S2.Na/c1-2(9)6-3-7-8-4(12-3)13(5,10)11;/h1H3,(H2,5,10,11)(H,6,7,9);

InChI key: InChIKey=LLRSVYADPZJNGD-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C=1SC(NC(C)=O)=NN1.[Na]

Synonyms:

• 1,3,4-Thiadiazole-2-sulfonamide, 5-acetamido-, sodium deriv.
• Acetamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-, monosodium salt
• Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-, monosodium salt
• Acetazolamide sodium salt
• Acetazolamidesodiumsalt
• Diamox Parenteral
• Diamoxsodium
• N-(5-(Aminosulfonyl)-1,3,4-Thiadiazol-2-Yl)-Acetamidmonosodiumsalt
• N-(5-Sulfamoyl-1,3,4-Thiadiazol-2-Yl)-Acetamidmonosodiumsalt
• N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
• Sodium acetazolamidate
• Sodium acetazolamide
• Sodium {[5-(Acetylamino)-1,3,4-Thiadiazol-2-Yl]Sulfonyl}Azanide
• Sodiumacetazolamide
• Vetamox
• acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-, sodium salt (1:1)

Acetazolamide sodium

CAS: 1424-27-7

Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.

Formula: C₄H₅N₄NaO₃S₂

Purity: 99.71% - 99.87%

Color and Shape: Solid

Molecular weight: 244.23

Ref: TM-T60351